DCE-MRI技术及ADC值对乳腺非肿块样强化病变良恶性的诊断价值  

Diagnostic value of DCE-MRI and ADC value in benign and malignant breast non-mass-like enhancement lesions

作　　者：徐静[1] 马光辉 孟凯龙[1] 王勇刚[1] 刘彭华[1] XU Jing;MA Guanghui;MENG Kailong;WANG Yonggang;LIU Penghua(CT Room,Handan First Hospital,Handan 056002,China;the Third Department of General Surgery,Handan First Hospital,Handan 056002,China)

机构地区：[1]邯郸市第一医院CT室,河北邯郸056002 [2]邯郸市第一医院普外三科,河北邯郸056002

出　　处：《中国医学物理学杂志》2023年第9期1132-1134,共3页Chinese Journal of Medical Physics

摘　　要：目的:探讨DCE-MRI技术及表观扩散系数(ADC)值对乳腺非肿块样强化(NMLE)病变良恶性的诊断价值。方法:回顾性分析180例在邯郸市第一医院接受手术并完成病理组织学诊断乳腺NMLE病变患者的临床资料,均行多模态3.0T MRI检查,比较良恶性病变MRI分布类型、强化特点、时间-信号曲线(TIC)类型及ADC值,描绘ROC曲线评价ADC值鉴别诊断效能。结果:恶性病变组节段型和集丛样强化比例显著高于良性病变组(P<0.05);两组TIC类型比较差异无统计学意义(P>0.05);恶性病变ADC值≤1.3×10^(-3)mm^(2)/s比例显著高于良性病变组(P<0.05);恶性病变ADC值显著小于良性病变组(P<0.05);描绘ROC曲线后分析,ADC值用于乳腺NMLE良恶性病灶鉴别诊断AUC=0.73,最佳cut-off值为1.3×10^(-3)mm^(2)/s,灵敏度和特异度分别为72.33%和79.60%。结论:DCE-MRI技术及ADC值可有效提高乳腺NMLE良恶性病灶的诊断效能,具有临床应用价值。Objective To investigate the clinical value of dynamic contrast-enhanced magnetic resonance imaging(DCEMRI)and apparent diffusion coefficient(ADC)value in the differential diagnosis of benign and malignant breast non-masslike enhancement(NMLE)lesions.Methods A retrospective analysis was carried out on 180 patients with breast NMLE lesions who underwent surgery and histopathological diagnosis in Handan First Hospital.All patients were scanned by multimodal 3.0T MRI.The distribution types,enhancement characteristics,time-intensity curve(TIC)types and ADC values of benign and malignant lesions were compared;and the efficiency of ADC value in the differential diagnosis of benign and malignant lesions was evaluated by receiver operating characteristic(ROC)curve.Results Compared with benign lesion group,malignant lesion group had higher proportions of segmental distribution,cluster like enhancement and ADC value≤1.3×10^(-3)mm^(2)/s,and lower ADC value(all P<0.05).There was no significant difference in TIC types between two groups(P>0.05).The ROC curve analysis showed that the AUC,sensitivity and specificity of ADC value in differentiating benign and malignant breast NMLE lesions were 0.73,72.33%and 79.60%,respectively,with the best cutoff value of 1.3×10^(-3)mm^(2)/s.Conclusion DCE-MRI and ADC value have clinical application value for they can effectively improve the diagnostic efficacy of benign and malignant breast NMLE lesions.

关 键 词：DCE-MRI 表观扩散系数 乳腺 非肿块样强化病变 鉴别诊断 

分 类 号：R737.9[医药卫生—肿瘤] R816.4[医药卫生—临床医学]