腹腔镜子宫肌瘤剔除术与经腹子宫肌瘤剔除术对子宫肌瘤的临床效果及安全性分析  

Clinical effect and safety analysis of laparoscopic and transabdominal myomectomy for uterine fibroids

作　　者：张明 ZHANG Ming(Department of Obstetrics and Gynecology,The Second People's Hospital of Wuxue,Wuxue 435411,China)

机构地区：[1]湖北省武穴市第二人民医院妇产科,435411

出　　处：《中国现代药物应用》2023年第18期60-63,共4页Chinese Journal of Modern Drug Application

摘　　要：目的研究腹腔镜子宫肌瘤剔除术与经腹子宫肌瘤剔除术对子宫肌瘤的临床效果及安全性。方法100例子宫肌瘤患者,按照随机数字表法分为对照组和观察组,每组50例。对照组实施经腹子宫肌瘤剔除术治疗,观察组实施腹腔镜子宫肌瘤剔除术治疗。比较两组手术指标、住院时间、临床疗效、并发症发生情况及手术前后应激指标[肾上腺素(E)、去甲肾上腺素(NE)]和卵巢功能指标[促卵泡刺激素(FSH)、雌二醇(E_(2))、促黄体生成素(LH)]。结果观察组术中出血量(77.39±10.13)ml少于对照组(100.60±15.73)ml,手术时间(64.72±4.48)min、术后肛门排气时间(18.08±2.14)h、住院时间(5.67±1.05)d均短于对照组的(81.54±6.69)min、(31.35±3.58)h、(10.56±2.14)d,差异具有统计学意义(P<0.05)。术后1 d,两组E、NE、FSH、LH水平均高于本组术前1 d,E_(2)水平低于本组术前1 d,但观察组E(108.01±15.63)pmol/L、NE(400.21±43.56)pmol/L、FSH(21.08±2.65)U/L、LH(18.78±2.60)U/L低于对照组的(175.35±18.76)pmol/L、(533.75±63.80)pmol/L、(27.29±3.37)U/L、(23.35±3.42)U/L,E_(2)(241.83±8.36)pmol/L高于对照组的(222.69±10.52)pmol/L,差异具有统计学意义(P<0.05)。观察组治疗总有效率为96.00%,高于对照组的82.00%,差异具有统计学意义(P<0.05)。观察组并发症发生率为6.00%,低于对照组的20.00%,差异具有统计学意义(P<0.05)。结论子宫肌瘤患者接受腹腔镜子宫肌瘤剔除术治疗的有效性及安全性均较经腹子宫肌瘤剔除术更高,应激反应更轻,对卵巢功能的影响小,值得临床推广应用。Objective To study the clinical effect and safety of laparoscopic and transabdominal myomectomy for uterine fibroids.Methods A total of 100 patients with uterine fibroids were divided into control group and observation group according to the random numerical table,with 50 cases in each group.The control group was treated with transabdominal myomectomy,and the observation group was treated with laparoscopic myomectomy.Both groups were compared in terms of surgical indexes,length of hospital stay,clinical efficacy,complications,stress indexes[epinephrine(E),noradrenaline(NE)]and ovarian function indexes[folliclestimulating hormone(FSH),estradiol(E_(2)),luteinizing hormone(LH)]before and after surgery.Results The intraoperative blood loss of(77.39±10.13)ml in the observation group was less than that of(100.60±15.73)ml in the control group;in the observation group,the operative time was(64.72±4.48)min,the postoperative anal exhaust time was(18.08±2.14)h,and the length of hospital stay was(5.67±1.05)d,which were shorter than those of(81.54±6.69)min,(31.35±3.58)h,and(10.56±2.14)d in the control group;the differences were statistically significant(P<0.05).At 1 d after surgery,E,NE,FSH,LH levels in both groups were higher than those at 1 d before surgery,and E2 level was lower than that at 1 d before surgery;the observation group had E of(108.01±15.63)pmol/L,NE of(400.21±43.56)pmol/L,FSH of(21.08±2.65)U/L,and LH of(18.78±2.60)U/L,which were lower than those of(175.35±18.76)pmol/L,(533.75±63.80)pmol/L,(27.29±3.37)U/L,and(23.35±3.42)U/L in the control group;E_(2) of(241.83±8.36)pmol/L in the observation group was higher than that of(222.69±10.52)pmol/L in the control group;the differences were statistically significant(P<0.05).The total effective rate of the observation group was 96.00%,which was higher than that of 82.00% of the control group,and the difference was statistically significant(P<0.05).The incidence of complications in the observation group was 6.00%,which was lower than that of 20.00% in th

关 键 词：子宫肌瘤 腹腔镜子宫肌瘤剔除术 经腹子宫肌瘤剔除术 卵巢功能 

分 类 号：R737.33[医药卫生—肿瘤]