机构地区:[1]泰安市妇幼保健院,271000 [2]山东省泰安荣军医院,271000
出 处:《中国现代药物应用》2023年第18期64-68,共5页Chinese Journal of Modern Drug Application
摘 要:目的观察儿童龋齿预防中采用窝沟封闭术联合氟保护漆的有效性。方法100例体检儿童,根据治疗差异将其分成对照组与观察组,每组50例(第一恒磨牙200颗)。对照组采取窝沟封闭术治疗,观察组采取窝沟封闭术联合氟保护漆。比较两组治疗前后龋齿情况、龈沟液炎性因子水平、情绪状态评分、咀嚼功能评分、适应行为评分。结果治疗后,观察组龋齿发生率9.00%低于对照组的25.50%,差异具有统计学意义(P<0.05)。治疗后,观察组Dickkopf相关蛋白-1(DKK-1)(6.35±2.21)μg/L、巨噬细胞炎症蛋白-1α(MIP-1α)(6.78±1.45)μg/L均低于对照组的(12.68±3.08)、(15.21±3.36)μg/L,差异具有统计学意义(P<0.05)。治疗后,观察组情绪识别评分(3.31±1.86)分、情绪管理评分(3.35±1.31)分、情绪应用评分(3.58±1.53)分均高于对照组的(2.40±1.15)、(2.21±1.56)、(2.87±1.65)分,差异具有统计学意义(P<0.05)。治疗后,观察组食物选择评分(6.81±1.39)分、咀嚼食物评分(6.86±1.45)分、咀嚼稳固度评分(6.88±1.27)分、咀嚼功能评分(6.86±1.39)分均高于对照组的(3.66±0.78)、(3.63±1.29)、(3.73±0.75)、(3.67±0.50)分,差异具有统计学意义(P<0.05)。治疗后,观察组感觉运动、生活自理、语言发展、个人取向、社会责任、时空定向、劳动体能、经济活动评分分别为(96.27±5.38)、(97.87±5.34)、(93.27±3.39)、(92.95±3.38)、(91.21±5.96)、(91.72±5.49)、(90.61±3.27)、(90.83±3.26)分,均高于对照组的(71.37±3.30)、(72.60±3.54)、(76.19±1.33)、(75.22±3.78)、(72.08±2.50)、(72.32±2.69)、(70.28±2.58)、(71.17±2.58)分,差异具有统计学意义(P<0.05)。结论窝沟封闭术联合氟保护漆治疗能够降低儿童龋齿的发生率,同时对其咀嚼功能、适应行为无不良影响。Objective To observe the effectiveness of fissure sealant combined with fluorine protective paint in the prevention of dental caries in children.Methods A total of 100 children who underwent examination were divided into a control group and an observation group based on treatment differences,with 50 children in each group(200 first permanent molars).The control group was treated with fissure sealant,and the observation group was treated with fissure sealant and fluorine protective paint.The dental caries,inflammatory factors in gingival crevicular fluid,emotional state score,masticatory function score and adaptive behavior score were compared between the two groups before and after treatment.Results After treatment,the incidence of dental caries of 9.00% in the observation group was better than that of 25.50% in the control group,the difference was statistically significant(P<0.05).After treatment,Dickkopf-1(DKK-1)of(6.35±2.21)μg/L and macrophage inflammatory protein-1α(MIP-1α)of(6.78±1.45)μg/L in the observation group were lower than those of(12.68±3.08)and(15.21±3.36)μg/L in the control group,and the differences were statistically significant(P<0.05).After treatment,in the observation group,the emotion recognition score was(3.31±1.86)points,the emotion management score was(3.35±1.31)points and the emotion application score was(3.58±1.53)points,which were higher than those of(2.40±1.15),(2.21±1.56)and(2.87±1.65)points in the control group,and the differences were statistically significant(P<0.05).After treatment,in the observation group,the food choice score was(6.81±1.39)points,the chewing food score was(6.86±1.45)points,the chewing stability score was(6.88±1.27)points and the chewing function score was(6.86±1.39)points,which were higher than those of(3.66±0.78),(3.63±1.29),(3.73±0.75)and(3.67±0.50)points in the control group,and the differences were statistically significant(P<0.05).After treatment,in the observation group,the scores of sensorimotor,self-care,language development,persona
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