结直肠癌活检病理诊断的应用价值  

Diagnostic Value of Biopsy Pathology in Colorectal Cancer

作　　者：曹怡静 刘超 CAO Yijing;LIU Chao(The Second Affiliated Hospital University of South China,Hunan Hengyang 421001)

机构地区：[1]南华大学附属第二医院,湖南衡阳421001

出　　处：《深圳中西医结合杂志》2023年第13期54-56,F0003,共4页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的:研究结直肠癌活检病理诊断的应用价值。方法:回顾性选取2022年5月至2023年4月南华大学附属第二医院收治的结直肠癌患者100例,术前均按照石蜡病理检查操作规范,借助肠道内窥镜获取的患者结肠、直肠病理组织活检样本开展病理学检查,并且术后有明确的手术病理诊断结果,对术前、手术病理诊断结果进行比较。结果:手术病理诊断结果显示100例结直肠癌患者中,结肠癌患者70例,直肠癌患者30例。在70例结肠癌患者中,病变部位为乙状结肠的有35例、为升结肠的有13例、为横结肠的有12例、为降结肠的有10例。100例患者的术前病理活检与手术病理诊断的符合率为98.00%,两种方法对不同类型结直肠癌的诊断结果比较,差异均无统计学意义(P> 0.05)。不同类型结直肠癌(腺癌、黏液腺癌、类癌)在病理活检下均能呈现出明显的组织学差异。结论:术前病理活检、手术病理诊断一致性较高,可将术前病理活检作为结直肠癌诊断及治疗的依据。Objective To study the diagnostic value of biopsy pathology in colorectal cancer.Methods A total of 100 patients with colorectal cancer admitted to the Second Affiliated Hospital University of South China from May 2022 to April 2023 were retrospectively selected.According to the operating norms of paraffin wax pathological examination before surgery,pathological biopsy samples of colon and rectum obtained by intestinal endoscope were carried out for pathological examination,and clear pathological diagnosis results were found after surgery.The results of preoperative and operative pathological diagnosis were compared.Results The pathological diagnosis of 100 patients with colorectal cancer showed that 70 patients with colon cancer and 30 patients with rectal cancer.Among the 70 cases of colon cancer,35 cases of sigmoid,13 cases of ascending colon,12 cases of transverse colon,and 10 cases of descending colon were affected.The coincidence rate between preoperative pathological biopsy and surgical pathological diagnosis of 100 patients was 98.00%,and there was no statistical significance between the two methods in the diagnosis of different types of colorectal cancer(P>0.05).Different types of colorectal cancer(adenocarcinoma,mucinous adenocarcinoma,carcinoid)can show significant histological differences under pathological biopsy.Conclusion Preoperative pathological biopsy is consistent with surgical pathological diagnosis.Preoperative pathological biopsy can be used as the basis for diagnosis and treatment of colorectal cancer.

关 键 词：结直肠癌 活检病理诊断 手术病理诊断 

分 类 号：R735.34[医药卫生—肿瘤] R361.2[医药卫生—临床医学]