Copper-catalyzed 1,4-protosilylation and 1,4-protoborylation of enynic orthoesters for synthesis of functionalized 2,3-allenoates  

作　　者：Qi Li Zi-Lu Wang Yun-He Xu 

机构地区：[1]Department of Chemistry,University of Science and Technology of China,Hefei 230026,China

出　　处：《Chinese Chemical Letters》2023年第9期151-155,共5页中国化学快报（英文版）

基　　金：the funding support of the National Natural Science Foundation of China(No.21871240);the Strategic Priority Research Program of the CAS(No.XDPB14);the Fundamental Research Funds for the Central Universities(No.WK2060190082)。

摘　　要：Herein,copper-catalyzed 1,4-protosilylation and 1,4-protoborylation of enynic orthoesters have been developed.The enynic orthoesters as precursors of unstable enynic esters were applied to produce the functionalized 2,3-allenoate products.Meanwhile,the asymmetric 1,4-protosilylation of enynic orthoesters with Ph Me2Si-Bpin was also studied.The chiral monopyridine imidazoline ligand was efficient to provide the asymmetric 1,4-protosilylation products with high enantioselectivity.

关 键 词：COPPER-CATALYZED 1 4-Protosilylation 1 4-Protoborylation 2 3-Allenoate Enynic orthoesters 

分 类 号：O621.251[理学—有机化学]