2种含漱液对远航人员慢性牙龈炎的疗效评价  

Evaluation of the therapeutic effects of two kinds of gargle on the patients with chronic gingivitis during prolonged deployment at sea

作　　者：张卓然 李凌 刘茵茵 董祺瑞 宋明芳 孙昊 Zhang Zhuoran;Li Ling;Liu Yinyin;Dong Qirui;Song Mingfang;Sun Hao(Department of Stamotology,Qingdao Special Service Sanatorium Center,Qingdao 266071,China)

机构地区：[1]海军青岛特勤疗养中心口腔科,山东青岛266071 [2]海军青岛特勤疗养中心康复科,山东青岛266071 [3]海军青岛特勤疗养中心疗养二区,山东青岛266071 [4]海军青岛特勤疗养中心医训部,山东青岛266071 [5]解放军96863部队

出　　处：《海军医学杂志》2023年第8期757-760,共4页Journal of Navy Medicine

基　　金：后勤保障部卫生保健专项课题(21BJZ05);青岛市医药科研指导计划(2020-WJZD202)。

摘　　要：目的评价2种含漱液在远航期间对慢性牙龈炎的疗效。方法从远航前口腔体检诊断为慢性牙龈炎的人员中随机选取80人作为研究对象,随机分为含漱A组(西帕依固龈液)、含漱B组(0.12%葡萄糖酸氯己定含漱液)、阴性对照组(清水漱口)和空白对照组,每组各20例。比较4组患者指数牙基线、使用含漱液2周后的菌斑指数(plaque index,PLI)、牙龈指数(gingival index,GI)和探诊出血(bleeding on probing,BOP)阳性牙位数。结果含漱B组2周后PLI、GI评分及BOP阳性牙位数分别下降0.28分、0.25分和0.70颗,差异均有统计学意义(P<0.05)。含漱A组仅有BOP阳性牙位数量下降了0.55颗,差异有统计学意义(P<0.05)。2个对照组2周后各临床指标差异均无统计学意义(P>0.05)。组间比较结果显示,4组间2周后PLI评分、GI评分及BOP阳性牙位数比较差异均有统计学意义(P<0.05)。经两两比较,含漱B组GI评分均低于其他3组(P<0.05),PLI评分及BOP阳性牙位数均低于2个对照组(P<0.05)。结论0.12%葡萄糖酸氯己定含漱液在远航条件下可以作为对牙菌斑和对牙龈炎的控制干预措施。Objective To evaluate the therapeutic effects of two kinds of gargle on chronic gingivitis during prolonged deployment at sea.Methods A total of 80 chronic gingivitis patients who experienced prolonged deployment at sea were enrolled for study and were randomly divided into 4 groups,depending upon the kinds of gargle used:Group A(the Xipayi gargle),Group B(the 0.12%chlorhexidine gargle),the negative control group(rinsing with running water)and the blank control group.The plaque index(PLI),the gingival index(GI)and bleeding on probing(BOP)were compared between the 4 groups.Results The scores of PLI,GI and BOP in the patients of group B decreased by 0.28,0.25 and 0.70 respectively after 2 weeks,with statistical significance(P<0.05).The BOP scores(0.55)of the patients in group A decreased by 0.55,also with statistical significance(P<0.05).After 2 two weeks of treatment,there were no statistic differences in clinical data,when comparisons were made between the two control groups(P>0.05).Two weeks after treatment,the mean scores of PLI,GI and BOP all displayed significant statistic differences,when comparisons were made between the four groups(P<0.05).The scores of GI in group B were higher than those of the other three groups(P<0.05).The scores of PLI and BOP were lower than those of the other two control groups(P<0.05).Conclusion Evidence shows that 0.12%chlorhexidine gargle could be used as an intervention measure against dental plaque and gingivitis during prolonged deployment at sea.

关 键 词：西帕依固龈液 氯己定 含漱液 远航 牙龈炎 牙菌斑 

分 类 号：R781.4[医药卫生—口腔医学]