相干光断层扫描血管成像在评估青光眼微循环改变中的应用  

Application of optical coherence tomography angiography on assessment of microcirculation changes in glaucoma

作　　者：张义晗 张凤妍[1] Zhang Yihan;Zhang Fengyan(Department of Ophthalmology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院眼科,郑州450052

出　　处：《国际眼科纵览》2023年第4期296-301,共6页International Review of Ophthalmology

摘　　要：相干光断层扫描血管成像(optical coherence tomography angiography,OCTA)是一种无创的眼科检查技术,能够提供高分辨率的微血管图像。青光眼的发病机制与眼底的血流密切相关。OCTA可对青光眼患者的视盘、视网膜及脉络膜血流灌注进行定量分析,并评估其微血管改变。不同类型的青光眼患者可出现视盘、视盘周围、黄斑区视网膜、脉络膜血管密度的下降及黄斑中心凹无血管区相关指标的异常,其改变与视野缺损程度、神经纤维层厚度及神经节细胞复合体厚度相关。Optical coherence tomography angiography(OCTA)is a novel,non-invasive ophthalmic examination technique that provides high-resolution images of microvascular.OCTA can quantitatively analyze optic disc,retinal and choroidal blood perfusion of patients with glaucoma and assess their microvascular changes.Patients with different types of glaucoma may have decreased vessel density of the optic disc,peripapillary,macular retina,choroid and abnormal indexes related to foveal avascular zone,whose changes are related to the degree of visual field defect,the thickness of the nerve fiber layer,and the thickness of the ganglion cell complex.

关 键 词：相干光断层扫描血管成像 青光眼 血管密度 黄斑中心凹无血管区 

分 类 号：R775[医药卫生—眼科]