Photochemical Nitration of Protected Anilines by 5-Methyl-1,4-dinitroimidazole  

作　　者：Xinlong Fan Yue Zhao Lei Liu Huan Wang 

机构地区：[1]State Key Laboratory of Coordination Chemistry,Chemistry and Biomedicine Innovation Center of Nanjing University,Jiangsu Key Laboratory of Advanced Organic Materials,School of Chemistry and Chemical Engineering,Nanjing University,Nanjing,Jiangsu,210023 China

出　　处：《Chinese Journal of Chemistry》2023年第13期1589-1593,共5页中国化学（英文版）

基　　金：supported by NSF of China(Grant 21922703 and 91953112 to H.W.);the Natural Science Foundation of Jiangsu Province(Grant BK20190004 and BK20202004);National Key R&D Program of China(2019YFA0905800).

摘　　要：Nitroanilines are important building blocks in pharmaceuticals,materials and dyes.Nitration methods for anilines under mild conditions are highly desired.Herein,we report a photochemical method for the nitration of anilines bearing various protecting groups by 5-methyl-1,4-dinitroimidazole as a new type of nitro source.This method is light-controlled and proceeds under mild reaction conditions with high efficiency.Fmoc-,Ts-and alkyl-protected anilines are all well nitrated with good functional group tolerance.

关 键 词：ANILINE Nitration Photocatalysis PHOTOCHEMISTRY Dinitroimidazole NITROANILINE PEPTIDOMIMETICS Radical reactions 

分 类 号：O641[理学—物理化学]