非酒精性脂肪性肝病与血管性认知损害  

Non-alcoholic fatty liver disease and vascular cognitive impairment

作　　者：华卉娟 梁玉霞 赵波 Hua Huijuan;Liang Yuxia;Zhao Bo(The First Clinical Medical College,Gansu University of Chinese Medicine,Lanzhou 730000,China;Department of Neurology,the 940th Hospital,Joint Logistic Support Force of Chinese PLA,Lanzhou 730050,China)

机构地区：[1]甘肃中医药大学第一临床医学院,兰州730000 [2]中国人民解放军联勤保障部队第九四〇医院神经内科,兰州730050

出　　处：《国际脑血管病杂志》2023年第6期456-461,共6页International Journal of Cerebrovascular Diseases

基　　金：联勤保障部队第九四〇医院研究生导师专项项目(2022yxky012)。

摘　　要：近年来,非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)与血管性认知损害(vascular cognitive impairment,VCI)之间的关系日益受到关注。二者相关的机制尚不明确,可能与神经炎症、氧化应激、脑血管病变、肠道菌群失调以及胰岛素抵抗等有关。文章对NAFLD与VCI的相关性及其潜在机制进行了综述,旨在为进一步探讨二者的相关性提供参考。In recent years,the relationship between non-alcoholic fatty liver disease(NAFLD)and vascular cognitive impairment(VCI)has received increasing attention.The mechanism underlying the relationship between the two diseases remains unclear,which may be associated with neuroinflamation,oxidative stress,cerebrovascular disease,gut microbiota imbalance,and insulin resistance.This article reviews the correlation and potential mechanisms between NAFLD and VCI,with the aim of providing reference for further exploration of their correlation.

关 键 词：非酒精性脂肪肝 认知障碍 痴呆 血管性 脑血管障碍 

分 类 号：R575.5[医药卫生—消化系统] R749.13[医药卫生—内科学]