FAL-1000A与Lenstar LS 900对眼生物学参数测量结果的一致性分析  

Consistency Analysis of Ocular Biometry Using FAL-1000A and Lenstar LS 900

作　　者：胡雅斌[1] 魏文斌[1] 翟长斌[1] 张丽[1] 付彩云 郑燕[1] Yabin Hu;Wenbin Wei;Changbin Zhai;Li Zhang;Caiyun Fu;Yan Zheng(Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Ophthalmology and Visual Sciences Key Laboratory,Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology,Beijing 100730,China)

机构地区：[1]首都医科大学附属北京同仁医院、北京同仁眼科中心、眼科学与视觉科学北京市重点实验室、工信部医学人工智能研究与验证实验室,北京100730

出　　处：《中华眼视光学与视觉科学杂志》2023年第9期665-670,共6页Chinese Journal Of Optometry Ophthalmology And Visual Science

基　　金：北京市科委科技计划项目(Z201100005520043、Z201100005520045)。

摘　　要：目的:评估国产眼生物测量仪FAL-1000A与进口眼生物测量仪Lenstar LS 900这2种设备测量屈光不正人群眼生物学参数的一致性。方法:系列病例研究。连续选取2022年8—9月在首都医科大学附属北京同仁医院眼科屈光手术中心就诊并符合入选标准的受检者386例(386眼)。采用国产眼生物测量仪FAL-1000A及进口眼生物测量仪Lenstar LS 900测量并记录眼轴长度(AL)、角膜平坦轴曲率(K1)、角膜陡峭轴曲率(K2)、平均角膜曲率(Km)、眼轴曲率比[眼轴/曲率半径(AL/CR)]等眼部生物学参数;并分别采用配对t检验、Pearson相关分析及Bland-Altman分析评估2种设备测量值的差异性、相关性及一致性。结果:FAL-1000A测量AL、K1,K2及AL/CR值均低于Lenstar LS 900的测量,差异均有统计学意义(均P<0.05)。FAL-1000A与Lenstar LS 900测量的AL、K1、K2、Km、AL/CR具有高度相关性(r=0.98、0.98、0.98、0.99、0.97,均P<0.001)。Bland-Altman分析显示AL、K1、K2、Km及AL/CR的95%一致性界限(95%LoA)分别为-0.247~0.164 mm、-0.366~0.529、-0.689~0.454、-0.412~0.372、-0.067~0.054,分别有3.6%、3.9%、3.6%、4.1%、3.1%点位于95%LoA之外,均显示2种设备获取生物学参数良好的一致性。结论:FAL-1000A作为1种新型的国产光学生物测量仪,与Lenstar LS 900测量的AL、角膜曲率、AL/CR等参数比较,具有良好的一致性,可用于屈光不正人群眼生物学参数评估。Objective:To evaluate the consistency of optical biometric parameters of adult subjects with refractive error measured by FAL-1000A and Lenstar LS 900.Methods:In this case series study,386 subjects(386 eyes)who planned to receive refractive surgery and met the enrollment criteria were recruited between August and September 2022 in the Beijing Tongren Eye Center.Axial length(AL),flat meridian keratometry(K1),steep meridian keratometry(K2),mean keratometry(Km),axial length/radii of corneal curvature(AL/CR)were measured using FAL-1000A and Lenstar LS 900.The difference,correlation,and agreement between the two instruments were analyzed by paired t-test,Pearson's correlation coefficient,and Bland-Altman plot,respectively.Results:AL,K1,K2,and AL/CR measured with FAL-1000A were significantly lower than that measured with Lenstar LS 900(all P<0.05).There was a good correlation for AL,K1,K2,Km,and AL/CR between two devices(r=0.98,0.98,0.98,0.99,0.97,all P<0.001).Bland-Altman analysis showed 95%limits of agreement(LoA)were-0.247-0.164 mm,-0.366-0.529,-0.689-0.454,-0.412-0.372,-0.067-0.054 for AL,K1,K2,Km and AL/CR,respectively.And there were 3.6%,3.9%,3.6%,4.1%,and 3.1%points of AL,K1,K2,Km,and AL/CR outside the 95%LOA,indicating good consistency of these two devices.Conclusions:As a domestic optical biometric measurement instrument,FAL-1000A showed a good agreement in measuring AL,K1,K2,Km,and AL/CR compared with Lenstar LS 900,and could be used for the evaluation of ocular biometry parameters in refractive error patients.

关 键 词：眼轴 角膜曲率 轴率比 FAL-1000A Lenstar LS 900 屈光不正 

分 类 号：R770.4[医药卫生—眼科]