白蛋白、前白蛋白与纤维蛋白原的比值在肿瘤中的研究进展  

Research progress of the ratio of albumin,prealbumin and fibrinogen in tumor

作　　者：张雪 张革红[2] ZHANG Xue;ZHANG Gehong(Shanxi Medical University,Shanxi Taiyuan 030000,China;Department of Oncology,the First Hospital of Shanxi Medical University,Shanxi Taiyuan 030000,China)

机构地区：[1]山西医科大学,山西太原030000 [2]山西医科大学第一医院肿瘤科,山西太原030000

出　　处：《现代肿瘤医学》2023年第20期3880-3884,共5页Journal of Modern Oncology

摘　　要：炎症反应和患者的机体状态被认为是肿瘤发生和发展中的一个重要标志,大部分患者就诊时就已经是中晚期,并且目前的诊断手段和检测手段较为昂贵、创伤较大,故找到易常规获取,对患者创伤小,并且能综合反映患者机体及肿瘤状态的指标显得尤为重要。其中,白蛋白-纤维蛋白原比值(albumin-to-fibrinogen ratio,AFR)、前白蛋白-纤维蛋白原比值(prealbumin-to-fibrinogen ratio,PFR)对肿瘤的预后有一定预测价值,有可能作为以后肿瘤患者治疗的一个独立预测因子,甚至优于其他炎症反应系统。但这些研究均为单中心、小样本研究且血清学指标的结果可能受多种因素影响,需进一步研究明确其价值。Inflammatory reaction and the state of patients are considered to be an important marker in the occurrence and development of tumor.Most patients are in the middle and late stage when they go to hospital,and the current diagnostic and testing methods are expensive and traumatic,so it is very important to find indicators that are easy to obtain routinely.Among them,albumin-to-fibrinogen ratio(AFR)and prealbumin-to-fibrinogen ratio(PFR)have certain predictive value for the prognosis of tumor.It may be used as an independent predictor of cancer treatment in the future,even better than other inflammatory response systems.However,these studies are single center and small sample studies,and the results of serological indicators may be affected by many factors,so further study is needed to clarify its value.

关 键 词：白蛋白 前白蛋白 纤维蛋白原 肿瘤 预后 

分 类 号：R730.4[医药卫生—肿瘤]