不同剂量二甲硅油散联合复方聚乙二醇电解质散进行肠道准备的清洁效果对比  

Comparison of cleaning effects of different doses of dimethyl silicone oil powder combinedwith compound polyethylene glycol electrolyte powder for intestinal preparation

作　　者：韦良宏 宁琳 潘际荣 劳雪莲 曾美美 谢彦飞 WEI Lianghong;NING Lin;PAN Jirong;LAO Xuelian;ZENG Meimei;XIE Yanfei(Deparment of Gastroenterololgy Two,the Tenth Affiliated Hospital of Guangxi Medical University—The First People's Hospital of Qinzhou,Qinzhou 535000,Guangxi,China)

机构地区：[1]广西医科大学第十附属医院暨广西钦州市第一人民医院消化二区,广西钦州535000

出　　处：《右江医学》2023年第9期800-804,共5页Chinese Youjiang Medical Journal

基　　金：钦州市科学研究与技术开发计划项目(20174305)。

摘　　要：目的探讨不同剂量二甲硅油散联合复方聚乙二醇电解质散进行肠道准备的清洁效果。方法选择拟行电子结肠镜检查患者150例。采用随机分组对照的研究方法,分为三组,A组口服复方聚乙二醇电解质散,B组口服复方聚乙二醇电解质散+2.5 g二甲硅油散,C组口服复方聚乙二醇电解质散+5 g二甲硅油散。观察各组间肠道清洁程度、祛泡效果、息肉检出率、胃肠道不良反应以及患者的接受度。结果三组肠道清洁度对比差异无统计学意义(P>0.05)。与A组相比,B组和C组的肠腔内气泡明显减少,差异有统计学意义(Z=-2.043,P=0.041;Z=-3.094,P=0.002);C组的息肉检出率明显高于A组,差异有统计学意义(χ2=6.205,P=0.012)。而B组和A组间的息肉检出率差异无统计学意义(χ2=4.372,P=0.062),加大二甲硅油散的用量可使腹胀发生率降低,差异有统计学意义(P=0.046)。结论5 g二甲硅油散联合复方聚乙二醇电解质散用于肠道清洁,可减少肠腔内气泡及腹胀,提高肠道息肉检出率,方法简单,值得推广。Objective To explore the clinical effects of different doses of dimethyl silicone oil powder combined with compound polyethylene glycol electrolyte powder for intestinal preparation.Methods 150 patients who planed to undergo electronic colonoscopy examination were selected.All patients were divided into group A,group B,and group C by randomized controlled study method.The group A were given oral compound polyethylene glycol electrolyte powder,the group B were given oral compound polyethylene glycol electrolyte powder+2.5 g of dimethyl silicone oil powder,and the group C were given oral compound polyethylene glycol electrolyte powder+5 g of dimethyl silicone oil powder.And then,the degree of intestinal cleanliness,defoaming effect,polyp detection rate,gastrointestinal adverse reactions,and patient acceptance among each group were observed.Results There was no statistically significant difference in intestinal cleanliness between the three groups(P>0.05).Compared with the group A,intraintestinal bubbles in the group B and the group C decreased significantly,and difference was statistically significant(Z=-2.043,P=0.041;Z=-3.094,P=0.002);the detection rate of polyps in the group C was significantly higher than that in the group A,and the difference was statistically significant(χ2=6.205,P=0.012).However,there was no statistically significant difference in the detection rate of polyps between the group B and the group A(χ2=4.372,P=0.062).Increasing the dosage of dimethyl silicone oil powder could reduce the incidence of abdominal distension,and the difference was statistically significant(P=0.046).Conclusion 5 g of dimethyl silicone oil powder combined with compound polyethylene glycol electrolyte powder for intestinal cleaning can reduce intraintestinal bubbles and abdominal distension,and improve the detection of intestinal polyps.The method is simple and worthy of promotion.

关 键 词：二甲硅油散 复方聚乙二醇电解质散 剂量 结肠镜 

分 类 号：R574[医药卫生—消化系统]