结直肠侧向发育型肿瘤伴结直肠息肉的临床特征初步分析  

Preliminary analysis of clinical features of colorectal laterally spreading tumor with colorectal polyps

作　　者：张曦予 刘淑妮 高云堃 张桂林 朱英嵽 黄华[1] 赵公芳[1] ZHANG Xi-yu;LIU Shu-ni;GAO Yun-kun;ZHANG Gui-lin;ZHU Ying-di;HUANG Hua;ZHAO Gong-fang(Department of gastroenterology,The Second Affiliated Hospital of Kunming Medical Univerity,Yunnan,Kunming,650101;Department of gastroenterology,Hanzhong People's Hospital,Shaanxi,Hanzhong,723000)

机构地区：[1]昆明医科大学第二附属医院消化内科,650101 [2]汉中市人民医院消化内科,723000

出　　处：《现代消化及介入诊疗》2023年第6期749-753,共5页Modern Interventional Diagnosis and Treatment in Gastroenterology

基　　金：云南省“万人计划”名医人才专项(YNWR-MY-2019-074);昆明医科大学第二附属医院院内科技计划项目(2021yk008)。

摘　　要：目的结直肠侧向发育型肿瘤(laterally spreading tumors,LST)和结直肠息肉均被认为是结直肠癌(colorectal cancer,CRC)的癌前病变,且LST常常伴随结直肠息肉发生发展。探索LST伴结直肠息肉的临床特征。方法对昆明医科大学第二附属医院2016年1月至2021年12月经结肠镜检查诊断为LST伴结直肠息肉95例,根据LST亚型、部位、大小、病理组织学各分为两组,进一步比较分析以上各组间在伴发结直肠息肉大小、部位、数量上的临床特征。结果1.LST-NG伴单发结直肠息肉的比例高于LST-G组(54.5%vs.22.6%)(P<0.05)。2.LST<3 cm伴<1 cm的结直肠息肉比例较高[(91.8%)vs.(50.0%)],LST≥3 cm伴有≥1 cm结直肠息肉比例高于LST<3 cm[(50.0%)vs.7(8.2%)](P<0.05)。3.近端结肠的LST多伴发近端结肠息肉(45.8%),远端结肠的LST多伴发远端结肠息肉(55.6%)(P<0.05)。4.LST恶性组和非恶性组在结直肠息肉的部位、数量、大小上均无差异统计学意义(P>0.05)。结论1.LST-NG伴单发结直肠息肉的比例较高,LST-G倾向于伴多发结直肠息肉。2.LST直径≥3 cm伴直径≥1 cm结直肠息肉比例较高,LST直径<3 cm伴有直径<1 cm的结直肠息肉比例更高。3.LST伴结直肠息肉时,结直肠息肉的好发部位与LST发病部位相似。Background:Laterally spreading tumors(LST)and colorectal polyps are not only considered as precancerous lesions of colorectal cancer,but LST also often accompanies the occurrence and development of colorectal polyps.Aims:To explore the clinical features of LST with colorectal polyps.Methods For 95 cases of LST with colorectal polyps diagnosed by colonoscopy in Kunming Medical University from Jan 2016 to Dec 2021,they were divided into two groups according to LST subtype,location,size and pathological histology,and the clinical characteristics in the size,location and number of colorectal polyp between the groups were further compared and analyzed.Results 1.LST-NG group had a higher proportion of single colorectal polyps than LST-G group(54.5%vs 22.6%)(P<0.05).2.LST<3 cm group had a higher proportion of colorectal polyps<1cm than LST≥3cm group(91.8%vs 50.0%).LST≥3 cm group had a higher proportion of colorectal polyps≥1 cm than LST<3cm group(50.0%vs 8.2%).(P<0.05).3.LST in the proximal colon was often associated with proximal colon polyps(45.8%),and LST in the distal colon was often associated with distal colon polyps(55.6%)(P<0.05).4.There was no significant difference in the location,number and size of colorectal polyps between the two groups(P>0.05).Conclusion 1.The proportion of LST-NG with single colorectal polyps is higher,and LST-G tends to have multiple colorectal polyps.2.The proportion of LST diameter<3 cm with colorectal polyps diameter<1 cm is higher,and the proportion of LST diameter≥3 cm with colorectal polyps diameter≥1 cm is higher.3.When LST is accompanied by colorectal polyps,the predilection site of colorectal polyps is similar to that of LST.

关 键 词：结直肠侧向发育型肿瘤 结直肠息肉 临床特征 

分 类 号：R574[医药卫生—消化系统]