新疆部分地区结直肠息肉患者的焦虑和抑郁状况及影响因素分析  

Analysis of anxiety and depressive status and influencing factors in patients with colorectal polyps in part of Xinjiang area

作　　者：谭雪娇 彭雅琼 彭昕[1] 骆苗苗 秦健[2] 李加学 冶丽娜 濮蓉晖[5] 赖力 马家静 张庆林 刘芳[1] 陈卫刚[1] Tan Xuejiao;Peng Yaqiong;Peng Xin;Luo Miaomiao;Qin Jian;Li Jiaxue;Ye Lina;Pu Ronghui;Lai Li;Ma Jiajing;Zhang Qinglin;Liu Fang;Chen Weigang(Department of Gastroenterology,the First Affiliated Hospital of Shihezi University,Shihezi 832000,China;Department of Gastroenterology,the Fourth Division Hospital of Xinjiang Production and Construction Corps,Yili 835000,China;Department of Digestive Oncology,the Third Division Hospital of Xinjiang Production and Construction Corps(Kashgar Hospital),Kashgar 844000,China;Department of Gastroenterology,the Thirteenth Division Red Star Hospital of Xinjiang Production and Construction Corps,Hami 839000,China;Department of Gastroenterology,the Tenth Division Beitun Hospital of Xinjiang Production and Construction Corps,Beitun 836099,China;Department of Gastroenterology,the Seventh Division Hospital of Xinjiang Production and Construction Corps,Kuitun 833200,China;Department of Gastroenterology,the Fifth Division Hospital of Xinjiang Production and Construction Corps,Bole 833400,China)

机构地区：[1]石河子大学第一附属医院消化内科,石河子832000 [2]新疆生产建设兵团第四师医院消化内科,伊犁835000 [3]新疆生产建设兵团第三师医院(喀什院区)消化肿瘤科,喀什844000 [4]新疆生产建设兵团第十三师红星医院消化内科,哈密839000 [5]新疆生产建设兵团第十师北屯医院消化科,北屯836099 [6]新疆生产建设兵团第七师医院消化内科,奎屯833200 [7]新疆生产建设兵团第五师医院消化内科,博乐833400

出　　处：《中华消化杂志》2023年第7期472-480,共9页Chinese Journal of Digestion

基　　金：兵团财政科技计划项目(2020CB002);石河子大学成果转化与技术推广计划项目(CGZH201704)。

摘　　要：目的调查新疆部分地区结直肠息肉患者焦虑和抑郁症状的发生情况,并探索可能与结直肠息肉患者心理状况相关的因素,为促进消化系统心身疾病的诊治提供依据和线索。方法纳入2021年12月至2022年6月在石河子大学第一附属医院、新疆生产建设兵团第四师医院、新疆生产建设兵团第三师医院(喀什院区)、新疆生产建设兵团第十三师红星医院、新疆生产建设兵团第十师北屯医院、新疆生产建设兵团第七师医院、新疆生产建设兵团第五师医院行结肠镜检查并检出结直肠息肉的患者。采用7项广泛性焦虑障碍量表(GAD-7)筛查焦虑症状、8项患者健康问卷(PHQ-8)筛查抑郁症状、一般情况调查表收集患者的临床信息。通过问卷星平台或纸质问卷完成问卷调查并建立数据库。按患者是否有焦虑、抑郁症状分组。应用多因素logistic回归模型分析与患者焦虑、抑郁相关的因素。结果共发放并回收516份问卷,其中填写不完整的问卷9份,有效问卷507份,问卷有效率98.26%。507例结直肠息肉患者的焦虑和抑郁症状检出率分别为21.50%(109/507)和19.33%(98/507)。多因素logistic回归分析显示,女性[OR=3.87,95%置信区间(95%CI)2.30~6.51,P<0.001]、息肉最大径(OR=1.74,95%CI 1.14~2.67,P=0.011)、认为息肉是癌的认知(OR=13.96,95%CI 1.48~132.07,P=0.022)、息肉检出后出现消化道症状(OR=5.43,95%CI 1.74~16.92,P=0.004)是结直肠息肉患者有焦虑症状的独立危险因素。女性(OR=2.42,95%CI 1.47~4.00,P=0.001)、息肉数量(OR=1.07,95%CI 1.01~1.13,P=0.028)、消化道症状种数(OR=2.04,95%CI 1.34~3.10,P=0.001)是结直肠息肉患者抑郁症状的独立危险因素。结论结直肠息肉患者的性别、息肉大小、息肉数量、疾病认知和合并消化道症状与焦虑、抑郁症状相关。ObjectiveTo investigated the prevalence of anxiety and depression symptoms in patients with colorectal polyps in part of Xinjiang area and to explore the associated influencing factors related to psychological status,and to provide evidence and clues to promote the diagnosis and treatment of psychosomatic diseases in digestive system.MethodsFrom December 2021 to June 2022,at the First Affiliated Hospital of Shihezi University,the Fourth Division Hospital of Xinjiang Production and Construction Corps,the Third Division Hospital of Xinjiang Production and Construction Corps(Kashgar Hospital),the Thirteenth Division Red Star Hospital of Xinjiang Production and Construction Corps,the Tenth Division Beitun Hospital of Xinjiang Production and Construction Corps,the Seventh Division Hospital of Xinjiang Production and Construction Corps,the Fifth Division Hospital of Xinjiang Production and Construction Corps,patients who underwent colonoscopy and colorectal polyps detected were enrolled.The generalized anxiety disorder scale-7(GAD-7)was used to screen anxiety symptoms,and the patient health questionaire-8(PHQ-8)was performed to screen depression symptoms,and the general situation questionnaire was used to collect clinical information of patients.The questionnairs were completed via the Questionnaire Star platform or paper questionnaire,and a database was established.The patients were divided into groups according to whether with anxiety and depression symptoms.Multivariable logistic regression models was performed to analyze the factors related to anxiety and depression.ResultsA total of 516 questionnaires were distributed and collected,among which 9 questionnaires were incomplete and 507 questionnaires were valid,the effective rate of questionnaires was 98.26%.The detection rates of anxiety and depression symptoms in 507 patients with colorectal polyps were 21.50%(109/507)and 19.33%(98/507),respectively.The results of multivariable logistic analysis revealed that female(OR=3.87,95%confidence interval(95%CI)2.30 to 6.5

关 键 词：结直肠息肉 焦虑 抑郁 影响因素 

分 类 号：R574.62[医药卫生—消化系统]