Axial length shortening in myopic children with Stickler syndrome after repeated low-level red-light therapy  

作　　者：Xiang-Hua Tang Meng-Ting Yu Yin Hu Ming-Guang He Xiao Yang 

机构地区：[1]State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangdong Provincial Clinical Research Center for Ocular Diseases,Guangzhou 510060,Guangdong Province,China [2]Centre for Eye Research Australia,Royal Victorian Eye and Ear Hospital,Melbourne,Victoria 3004,Australia [3]Ophthalmology,Department of Surgery,University of Melbourne,Melbourne,Victoria 3004,Australia

出　　处：《International Journal of Ophthalmology(English edition)》2023年第10期1712-1717,共6页国际眼科杂志（英文版）

摘　　要：AIM:To report the myopia-controlling effect of repeated low-level red-light(RLRL)therapy in patients with Stickler syndrome(STL),an inherited collagenic disease typically presenting with early onset myopia.METHODS:Three STL children,aged 3,7,and 11y,received RLRL therapy throughout the follow-up period of 17,3,and 6mo,respectively after exclusion of fundus anomalies.Data on best-corrected visual acuity(BCVA),intraocular pressure,cycloplegic subjective refraction,ocular biometrics,scanning laser ophthalmoscope,optical coherence tomography,genetic testing,systemic disease history,and family history were recorded.RESULTS:At the initiation of the RLRL therapy,the spherical equivalent(SE)of 6 eyes from 3 patients ranged from-3.75 to-20.38 D,axial length(AL)were from 23.88 to 30.68 mm,and BCVA were from 0.4 to 1.0(decimal notation).Myopia progression of all six eyes slowed down after RLRL therapy.AL in five out of the six eyes shortened-0.07 to-0.63 mm.No side effects were observed.CONCLUSION:Three cases of STL whose progression of myopic shift and AL elongation are successfully reduced and even reversed after RLRL therapy.

关 键 词：Stickler syndrome axial length shortening MYOPIA repeated low-level red-light therapy 

分 类 号：R770.4[医药卫生—眼科]