729例慢性胃炎患者幽门螺杆菌感染现状及中医证型分布情况  

Prevalence of Helicobacter pylori infection among 729 patients with chronic gastritis and types of traditional Chinese medicine syndromes

作　　者：许冰 王梁敏[2] 刘苗 胡海荣 韩海啸[1] 李艳林 陈默岩 徐婧 XU Bing;WANG Liang-min;LIU Miao;HU Hai-rong;HAN Hai-xiao;LI Yan-lin;CHEN Mo-yan;XU Jing(Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078,China)

机构地区：[1]北京中医药大学东方医院脾胃肝胆科,北京100078 [2]北京中医药大学东方医院呼吸热病科,北京100078 [3]北京中医药大学东方医院护理部,北京100078 [4]北京中医药大学东方医院药学部,北京100078

出　　处：《中华医院感染学杂志》2023年第18期2773-2776,共4页Chinese Journal of Nosocomiology

基　　金：首都卫生发展科研专项项目(2018-1-4072)。

摘　　要：目的对幽门螺杆菌(Hp)相关性胃炎患者感染现状、变化趋势及中医证型进行分析,为实施辨证治疗及护理提供科学依据.方法以2019年1月-2021年12月就诊于北京中医药大学东方医院诊断为慢性胃炎并进行13C-UBT检测Hp的患者729例作为研究对象,明确Hp检查结果,收集患者一般资料,对感染现状及中医证型进行分析.结果729例慢性胃炎患者,男性和女性Hp阳性率分别为28.47%和23.81%,比较差异无统计学意义;不同年龄段患者Hp阳性率比较有统计学差异(P<0.05),其中>30~60岁阳性率较高,>70岁阳性率较低;各不同饮食习惯人群Hp阳性率比较无统计学意义,但进食油炸食品阳性率较高;中医证型中脾胃湿热证患者Hp阳性率较高,达到38.64%,其次为肝胃不和证和脾胃气虚证,Hp阳性率分别为22.42%和21.43%.结论近3年来慢性胃炎就诊患者Hp阳性率呈下降趋势,>30~60岁患者Hp阳性率较高,且脾胃湿热证为首要中医证型.OBJECTIVE To investigate the prevalence of Helicobacter pylori(Hp)infection among the patients with chronic gastritis,observe the variation trends and analyze the types of traditional Chinese medicine(TCM)syndromes so as to provide scientific bases for treatment and nursing based on syndrome differentiation.METHODS Totally 729 patients with chronic gastritis who were treated in Dongfang Hospital,Beijing University of Chinese Medicine and received 13C-UBT test for Hp from Jan 2019 to Dec 2021 were recruited as the research subjects,the result of Hp test was made clear,the baseline data were collected from the patients,and the current status of the infection and types of TCM syndromes were analyzed.RESULTS Among the 729 patients with chronic gastritis,the positive rate of Hp was 28.47%in male patients,23.81%in female patients,and there was no significant difference;there was significant difference in the positive rate of Hp among the different age groups of patients(P<0.05),the positive rate was relatively high among the patients aged between 30 and 60 years old,and the positive rate was relatively low among the patients aged more than 70 years old.There was no significant difference in the positive rate of Hp among the patients who had different dietary habits,and the positive rate was relatively high among the patients who ate fried food.The positive rate of Hp in patients with spleen stomach dampness heat syndrome in traditional Chinese medicine is relatively high,reaching 38.64%,followed by liver stomach disharmony syndrome and spleen stomach qi deficiency syndrome,with Hp positive rates of 22.42%and 21.43%,respectively.CONCLUSION The positive rate of Hp shows a downward trend among the chronic gastritis patients in the recent 3 years,the positive rate of Hp is relatively high among the patients aged between 30 and 60 years old,and the damp heat in spleen and stomach is the primary TCM syndrome.

关 键 词：幽门螺杆菌 感染 慢性胃炎 饮食习惯 中医证型 

分 类 号：R573.3[医药卫生—消化系统]