0.05 D精准足矫技术与多区正向光学离焦技术在延缓近视进展中的协同作用研究  

Study on the synergistic effect of 0.05 D precision full correction technique and defocus incorporated multiple segments technique in delaying the progress of myopia

作　　者：甄毅[1] 曹凯[1] 高杰 王宁利[1] Zhen Yi;Cao Kai;Gao Jie;Wang Ningli(National Engineering Research Center for Ophthalmology,Beijing Institute of Ophthalmology,Beijing Tongren Eye Center,Engineering Research Center of the Ministry of Education for Ophthalmic Diagnosis and Treatment Equipment and Materials,Beijing Tongren Hospital,Capital Medical University,Beijing Key Laboratory of Ophthalmology and Visual Science,Beijing 100730,China;Beijing Tianming Ophthalmology New Technology Development Company,Beijing 100730,China)

机构地区：[1]首都医科大学附属北京同仁医院、北京同仁眼科中心、北京市眼科研究所、国家眼科诊断与治疗工程技术研究中心、眼科诊疗设备与材料教育部工程研究中心、眼科学与视觉科学北京市重点实验室,100730 [2]北京天明眼科新技术开发公司,100730

出　　处：《眼科》2023年第4期282-286,共5页Ophthalmology in China

基　　金：北京市科技计划(Z201100005520042);北京大数据精准医疗高精尖创新中心计划。

摘　　要：目的 观察0.05 D精准足矫技术与多区正向光学离焦技术在延缓近视进展中是否存在协同作用。设计前瞻性比较性病例系列。研究对象2020-2022年北京同仁医院验配中心验配框架眼镜的241例儿童。方法根据家长对镜片的选择,患儿分为0.05 D球镜间隔单光组63例、0.25 D球镜间隔单光组57例、0.25 D球镜间隔离焦组61例、0.05 D球镜间隔离焦组60例。对电子病历系统中儿童配镜资料进行回顾分析。提取年龄、性别、屈光度、前后两次验光的间隔时间、镜片类型等信息。4组患者的验光方法与环境均一致,差别仅为框架眼镜镜片中央是否使用0.05 D精准足矫技术及镜片周边是否使用多区正向光学离焦技术。取右眼数据统计分析。主要指标等效球镜度变化。结果0.25 D球镜间隔单光组、0.05 D间隔单光镜片组、0.25 D球镜间隔离焦组和0.05 D间隔离焦组的年龄无差异(F=0.996,P=0.320);第一次配镜时等效球镜度数均值分别为(-2.10±1.77)D、(-2.00±1.34)D、(-1.97±0.89)D和(-2.03±0.88)D(F=0.118,P=0.949)。戴镜6个月后4组患者的等效球镜度变化值分别为(-0.51+0.52)D、(-0.31±0.35)D、(-0.31±0.27)D和(-0.15±0.26)D(F=9.503,P<0.001)。0.05 D间隔单光组(P=0.003)、0.25 D间隔离焦组(P=0.004)、0.05 D间隔离焦组(P<0.001)的等效球镜变化均明显小于0.25 D间隔单光组。0.05 D间隔单光组和0.25 D间隔离焦组的等效球镜度变化无显著差别(P=0.932)。0.05 D间隔离焦组的等效球镜度变化明显小于0.05 D间隔单光组(P=0.018)和0.25 D间隔离焦组(P=0.015)。结论0.05 D精准足矫技术与多区正向光学离焦技术在延缓近视进展方面因作用途径不同而显示出相加协同作用。Objective To observe whether there is a synergistic effect between 0.05 D precise full correction technology and defocus incorporated multiple segments technology in delaying myopia progression.Design Pretrospective comparative case series.Participants 241 children who underwent frame glasses fitting at Optometry Center of Beijing Tongren Hospital from 2020 to 2022.Method According to the lens chosen by the parents,241 children were fitted with 0.05 D spherical interval single vision group(63 cases),0.25 D spherical interval single vision group(57 cases),0.25 D spherical interval defocus group(61 cases),and 0.05 D spherical interval defocus group(60 cases).The fitting data including age,gender,refractive error,interval time between the two refractions,lens type of the above children in the electronic medical record system was retrospective analyzed.The refraction methods and environment of the four groups of patients were consistent,and the only difference was whether 0.05 D precise full correction technology was used in the central area of the frame eyeglasses and whether defocus incorporated multiple segments technology was used in the periphery of the lens.The data of the right eye were analyzed statistically.Main Outcome Measures Equivalent spherical change.Results The ages of the 0.25 D spherical interval single vision group,the 0.05 D interval single vision lens group,the 0.25 D spherical interval defocus group,and the 0.05 D interval defocus group were not significantly different(F=0.996,P=0.320).The mean equivalent spherical degrees at the first visit were(-2.10±1.77)D,(-2.00±1.34)D,(-1.97±0.89)D,and(-2.03±0.88)D,respectively(F=0.118,P=0.949).After 6 months of wearing glasses,the equivalent spherical changes in the four groups of patients were(-0.51±0.52)D,(-0.31±0.35)D,(-0.31±0.27)D,and(-0.15±0.26)D,respectively(F=9.503,P<0.001).The equivalent spherical changes in the 0.05 D interval single vision group(P=0.003),the 0.25 D interval defocus group(P=0.004),and the 0.05 D interval defocus group(P<0.

关 键 词：近视 0.05 D精准足矫技术 多区正向光学离焦技术 

分 类 号：R778.11[医药卫生—眼科]