免疫性因素所致癫间发作及免疫相关性癫间的研究进展  

Review on Symptomatic Seizures and Immune-associated Epilepsy Caused by Immune Etiology

作　　者：肖潇 汤继宏[1] XIAO Xiao;TANG Ji-hong(Department of Neurology,Children's Hospital of Soochow University,Suzhou 215025,China)

机构地区：[1]苏州大学附属儿童医院神经内科,苏州215025

出　　处：《中国临床神经科学》2023年第4期435-441,共7页Chinese Journal of Clinical Neurosciences

基　　金：江苏省卫生健康委科技课题面上项目(编号:H2018010);苏州市“科教兴卫”青年科技项目(编号:KJXW2019023)。

摘　　要：免疫性因素与癫间发作及癫间的关系日益受到重视。为了明确免疫因素所致癫间发作及癫间的临床特点及预后,国际抗癫间联盟于2020年发布了新概念:继发于自身免疫性脑炎的急性症状性发作(acute symptomatic seizures secondary to autoimmune encephalitis)及自身免疫相关性癫间(autoimmune-associated epilepsy)。文中就这一新概念进行解读及阐述,并总结了与癫间发作密切相关的一系列自身免疫性脑炎及免疫相关性癫间的临床特点,以进一步提高对这些疾病的认识。The immune etiology of epilepsy has been highly concerned recently.In order to improve the understanding of the characteristics,treatments,and prognosis in autoimmune caused epilepsy,the International League Against Epilepsy(ILAE)released the new concepts in 2020:acute symptomatic seizures secondary to autoimmune encephalitis,and autoimmune-associated epilepsy.The two new definitions were interpreted and elaborated,and the clinical characteristics of a series of autoimmune encephalitis and immune-associated epilepsy were reviewed.

关 键 词：免疫 癫间发作 癫间 自身免疫性脑炎 

分 类 号：R742.1[医药卫生—神经病学与精神病学]