经股动脉介入对急性脑梗死患者血管再通率的影响研究  

Effect of femoral artery intervention on vascular recanalization rate in patients with acute cerebral infarction

作　　者：赵菲 孙泽西 白永杰[2] ZHAO Feil;SUN Ze-xi;BAI Yong-jie(Imaging Center,the First Affiliated Hospital of Henan University of Science and Technology,Luoyang,Henan 471000,China;Department of Neurology,the First Affiliated Hospital of Henan University of Science and Technology,Luoyang,Henan 471000,China)

机构地区：[1]河南科技大学第一附属医院影像中心,河南洛阳471000 [2]河南科技大学第一附属医院神经内科,河南洛阳471000

出　　处：《医药论坛杂志》2023年第16期17-20,24,共5页Journal of Medical Forum

基　　金：河南省卫生健康科技英才海外研修工程计划(HWYX2019091)。

摘　　要：目的研究急性脑梗死患者采用经股动脉介入治疗的效果及对血管再通率的影响。方法纳入河南科技大学第一附属医院2020年1月至2021年12月收治的84例患者作为研究对象,应用随机数字表法分为对照组和观察组,每组42例。对照组采用静脉溶栓治疗,观察组采用经股动脉介入治疗,对比两组治疗前后脑血流动力学和神经功能指标,统计两组治疗后血管再通情况。结果对比发现观察组血管再通率高于对照组(χ^(2)=3.896,P=0.048);治疗前两组治疗前R、Qmean、Vmean、NSE、S100B、SDF-1和VILIP-1无显著差异(P>0.05);治疗后观察组R、NSE、S100B和VILIP-1低于对照组(t=2.631,4.120,4.971,3.081;P=0.010,<0.001,<0.001,0.003),Qmean、Vmean、SDF-1高于对照组(t=2.685,2.420,3.955;P=0.009,0.018,<0.001)。结论研究发现,经股动脉介入治疗急性脑梗死的效果显著,血管再通率高,对患者脑血流动力学和神经功能改善效果良好,可有效的提高临床治疗的有效性,改善患者预后效果。Objective To study the effect of femoral artery interventional therapy and its effect on vascular recanalization rate in patients with acute cerebral infarction.Methods A total of 84 patients admitted to our hospital from January 2020 to December 2021 were included as the study subjects,and were divided into control group and observation group by random number table method,with 42 patients in each group.The control group was treated with intravenous thrombolytic therapy,and the observation group was treated with femoral artery interventional therapy.The cerebral hemodynamics and neurological function indexes of the two groups were compared before and after treatment,and the vascular recanalization of the two groups after treatment was counted.Results The revascularization rate of the observation group was higher than that of the control group(χ^(2)=3.896,P=0.048).Before treatment,there were no significant differences in R,Qmean,Vmean,NSE,S100B,SDF-1 and VILIP-1 between the two groups(P<0.05).After treatment,R,NSE,S100B and VILIP-1 in the observation group were lower than those in the control group(t=2.631,4.120,4.971,3.081;P=0.010,0.001,0.001,0.003),Qmean,Vmean and SDF-1 were higher than those in control group(t=2.685,2.420,3.955;P=0.009,0.018,0.001).Conclusion The study found that the femoral artery interventional treatment of acute cerebral infarction has a significant effect,high vascular recanalization rate,and good effect on the improvement of cerebral hemodynamics and neurological function.

关 键 词：经股动脉介入 急性脑梗死 治疗效果 血管再通率 

分 类 号：R743.3[医药卫生—神经病学与精神病学]