胸水细胞蜡块结合免疫组织化学染色技术诊断肺癌的临床意义  被引量:1

Clinical Significance of Pleural Fluid Cell Wax Blocks Combined with Imunohistochemical Staining Technique for Diagnosis of Lung Cancer

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作  者:张玉春 戴陆春 ZHANG Yuchun;DAI Luchun(Department of Respiratory and Critical Care Medicine,Suining County People's Hospital,Suining,Jiangsu Province,221200 China)

机构地区:[1]睢宁县人民医院呼吸与危重医学科,江苏睢宁221200

出  处:《系统医学》2023年第15期71-74,共4页Systems Medicine

摘  要:目的分析胸水细胞蜡块结合免疫组织化学染色技术诊断肺癌的价值。方法选取2021年5月—2023年3月睢宁县人民医院收治的疑似肺癌患者67例为研究对象,均给予液基细胞学、细胞蜡块结合免疫组化检测,以病理检查结果为金标准,比较不同检测方法诊断效能以及对不同类型肺癌的鉴别准确性。结果67例患者中经病理检查确诊肺癌47例、良性病变20例,细胞蜡块结合免疫组织化学染色检查灵敏度、特异度、准确性、阳性预测值、阴性预测值均高于液基细胞学检测结果。以病理检查为金标准,细胞蜡块结合免疫组织化学染色检测对于腺癌诊断符合率100.00%,高于液基细胞学检测的78.95%,差异有统计学意义(χ^(2)=6.846,P<0.05)。结论肺癌诊断中,以胸水细胞蜡块结合免疫组化检测技术应用价值较高,除进行肺癌检出之外,还可进行肿瘤类型鉴别。Objective To analyze the value of pleural fluid cell wax block combined with immunohistochemical staining technique in diagnosing lung cancer.Methods Sixty-seven patients with suspected lung cancer admitted to Suining County People's Hospital from May 2021 to March 2023 were selected as the study objects.All of them were given liquid-based cytology and cell wax block combined with immunohistochemical detection,with pathological examination results as the gold standard.The diagnostic efficiency and accuracy of different detection methods for different types of lung cancer were compared.Results Among the 67 patients,47 cases of lung cancer and 20 cases of benign lesions were confirmed by pathological examination.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of cell wax block combined with immunohistochemical staining were higher than those of liquid based cytology.With pathological examination as the gold standard,the coincidence rate of cell wax block combined with immunohistochemical staining was 100.00%,which was higher than that of liquid cytology(78.95%),and the difference was statistically significant(χ^(2)=6.846,P<0.05).Conclusion In the diagnosis of lung cancer,pleural fluid cell wax block combined with immunohistochemistry detection technology has a higher application value,and in addition to lung cancer detection,it can also be used to identify the tumor type.

关 键 词:胸水细胞蜡块 免疫组织化学染色技术 肺癌 诊断 

分 类 号:R734[医药卫生—肿瘤]

 

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