轻型缺血性脑卒中认知功能障碍发生情况及其影响因素分析  

Analysis of Cognitive Dysfunction in Mild Ischemic Stroke and Its Influencing Factors

作　　者：朱琳[1] 吕逸宁 ZHU Lin;LYU Yining(Department of Comprehensive Internal Medicine,Beijing Second Hospital,Beijing,100000 China;Department of Geriatric,Huaxin Hospital,Beijing,100016 China)

机构地区：[1]北京市第二医院综合内科,北京100000 [2]华信医院老年科,北京100016

出　　处：《系统医学》2023年第15期117-120,共4页Systems Medicine

摘　　要：目的探讨分析轻型缺血性脑卒中认知功能障碍发生情况及其影响因素。方法选取2021年1月—2023年2月北京市第二医院收治的轻型缺血性脑卒中患者99例为研究对象,采用简易精神状态量表对是否有认知功能障碍进行分组,分为认知障碍组28例和认知正常组71例,对其影响因素进行分析。结果经单因素分析显示,认知障碍组年龄、高血压、衰弱、受教育水平、超敏C反应蛋白、脑梗死病史以及脑白质疏松发生率、梗死部位与认知正常组比较,差异有统计学意义(P<0.05)。经Logistic多因素回归分析显示,梗死部位、年龄、脑梗死病史、衰弱、高血压、脑白质疏松、超敏C反应蛋白是认知功能障碍发生的独立危险因素(OR=1.184、1.092、1.145、1.173、1.094、1.043、1.133,P<0.05)。结论轻型缺血性脑卒中的认知功能障碍发生率依然较高,梗死部位、年龄、脑梗死病史、衰弱、高血压、脑白质疏松、超敏C反应蛋白是知功能障碍发生的独立危险因素,需要临床予以重视,及时防止认知功能障碍发生。Objective To investigate the incidence and influencing factors of cognitive dysfunction in mild ischemic stroke.Methods 99 patients with mild ischemic stroke admitted to Beijing Second Hospital from January 2021 to February 2023 were selected as the study objects,and cognitive dysfunction was classified by simple mental state scale.There were 28 cases of cognitive dysfunction group and 71 cases of normal cognitive group,and the influencing factors were analyzed.Results Univariate analysis showed between the cognitive dysfunction group and the normal cognitive group in terms of age,hypertension,frailty,education level,hypersensitive C-reactive protein,history of cerebral infarction,incidence of white matter osteoporosis,infarct site,the difference was statistically significant(P<0.05).By Logistic multifactor regression analysis showed that the infarction area,age,history of cerebral infarction,weak,high blood pressure,cerebral white matter loose,hypersensitive c-reactive protein were independent risk factors of dysfunction occurs(OR=1.184,1.092,1.145,1.173,1.094,1.043,1.133,P<0.05).Conclusion The incidence of cognitive dysfunction in mild ischemic stroke is still high.Infarction site,age,history of cerebral infarction,frailty,hypertension,white matter osteoporosis and hypersensitive C-reactive protein are independent risk factors for the occurrence of cognitive dysfunction,which need clinical attention and timely prevention and treatment of cognitive dysfunction.

关 键 词：缺血性脑卒中 认知功能障碍 发生情况 影响因素 

分 类 号：R743[医药卫生—神经病学与精神病学]