Chemical constituents and anticoagulant activity from Delphinium brunonianum Royle  

作　　者：Changyang Ma Sitan Chen Syed Arif Hussain Rizvi Huihui Zhou Wenyi Kang Xuefeng Xi Zhenhua Liu 

机构地区：[1]National R&D Center for Edible Fungus Processing Technology,Henan University,Kaifeng 475004,China [2]Joint International Research Laboratory of Food&Medicine Resource Function,Henan Province,Kaifeng 475004,China [3]Pakistan Agricultural Research Council,Islamabad 450000,Pakistan [4]College of Physical Education,Henan University,Kaifeng 475004,China

出　　处：《Journal of Future Foods》2024年第3期241-247,共7页未来食品学报（英文）

基　　金：This work was funded by Research on Precision Nutrition and Health Food,Department of Science and Technology of Henan Province(CXJD2021006).

摘　　要：Delphinium brunonianum Royle belongs to Ranunculaceae family and has the effects of dispelling wind to relieve itching and cooling blood to detoxify.It was found that the extracts of D.brunonianum had good anticoagulant activity which was extracted with 70%ethanol in our previous researches.Then,16 compounds were isolated and identified from the extract of D.brunonianum,among which compounds 5,7-10,12,14,15-16 were isolated from this genus for the first time,and compounds 2-4 were isolated from this plant for the first time.And the coagulation activity assay showed that compounds 10,14 and 15 had good anticoagulant activity by activated partial thromboplastin time(APTT),thrombin time(TT)and prothrombin time(PT)in vitro.

关 键 词：Delphinium brunonianum Royle 9-Hydroxy-megastigma-4 7-dien-3-one-9-β-Dglucopyranoside 4-O-α-D-Glucosyl benzoic acid Isolariciresinol 4-O-β-D-glucopyranoside Anticoagulant activity 

分 类 号：TS201[轻工技术与工程—食品科学]