Novel colorimetric,photothermal and up-conversion fluorescence triple-signal sensor for rosmarinic acid detection  

作　　者：Yinyin Chen Xiujuan Yang Changfang Lu Zouping Yang Wei Wu Xianxiang Wang 

机构地区：[1]College of Agronomy,Sichuan Agricultural University,Chengdu 611130,China [2]College of Science,Sichuan Agricultural University,Chengdu 611130,China [3]State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China,Chengdu 611130,China

出　　处：《Chinese Chemical Letters》2023年第8期275-281,共7页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.21305097);General Project of Education Department in Sichuan(No.035Z2270);Sichuan Key Discipline Construction Project of Traditional Chinese Medicine(No.2021-16-4);Double-Support Plan of Disciplinary Construction in Sichuan Agricultural University-Innovation Team Projects(No.P202108).

摘　　要：Rosmarinic acid(RA)is promising as a natural and nontoxic food additive.However,many analysis methods for RA generally depend on large instruments and single signals for quantitative detection.A new upconversion fluorescence,colorimetric and photothermal multi-modal sensing strategy is developed for the quantification of RA.β-cyclodextrin(CD)modified citric acid(Cit)wrapped NaYF_(4):Yb/Er-Cit-CD(Y:Yb/Er-Cit-CD)up-conversion nanocomposite has been synthesized,which emits green fluorescence at 550nm under 980nm near-infrared(NIR)excitation.In the presence of oxidized 3,3',5,5'-tetramethylbenzidine(oxTMB),the green fluorescence is significantly quenched attributed to the fluorescence inner filter effect(IFE)between oxTMB and Y:Yb/Er-Cit-CD.When RA is intervened,blue oxTMB is reduced to colorless 3,3',5,5'-tetramethylbenzidine(TMB)inducing the recovery of up-conversion fluorescence.At the same time,colorimetric and photothermal signals readout can be easily achieved thanks to the color indication and photothermal effect of the oxTMB.The constructed Y:Yb/Er-Cit-CD/oxTMB sensor displays high sensitivity,visibility and simplicity for RA,and the limits of detection(LOD)for fluorescence,colorimetric and photothermal were 0.004μmol/L,0.036μmol/L and 0.043μmol/L,respectively.This sensing system is successfully performed for the detection of RA in food samples.

关 键 词：Multi-modal sensing Up-conversion fluorescence COLORIMETRIC PHOTOTHERMAL Rosmarinic acid 

分 类 号：TS207.3[轻工技术与工程—食品科学] O657.3[轻工技术与工程—食品科学与工程]