包裹性与浸润性滤泡型甲状腺乳头状癌的超声及临床特征分析  

Analysis of Ultrasonic and Clinical Features of Encapsulated and Invasive Encapsulated Follicular Variant Papillary Carcinoma

作　　者：吴月 齐祥飞 周爱云[1] 戚琪 李耀辉 徐盼[1] Wu Yue;Qi Xiangfei;Zhou Aiyun;Qi Qi;Li Yaohui;Xu Pan(Department of Ultrasound Medicine,The First Affiliated Hospital of Nanchang University,Nanchang 330006,China)

机构地区：[1]南昌大学第一附属医院超声医学科,南昌市330006

出　　处：《中国超声医学杂志》2023年第9期966-969,共4页Chinese Journal of Ultrasound in Medicine

基　　金：江西省自然科学基金(No.20224BAB216079)。

摘　　要：目的探究两种滤泡型甲状腺乳头状癌(FVPTC)的超声表现、临床特征及其与颈部淋巴结转移的相关性。方法回顾性分析经病理证实的82例FVPTC患者,其中包裹性组(EFVPTC)31例,浸润性组(IEFVPTC)51例,并纳入50例经典型乳头状癌(CPTC)患者对比,分析其超声及临床特征,在FVPTC组间探讨与颈部淋巴结转移的相关性。结果IEFVPTC组与EFVPTC组在最大径、血流信号、颈部淋巴结转移率间差异有统计学意义(P<0.05)。两亚组FVPTC与CPTC组在丰富血流、极低回声、中国超声甲状腺影像报告和数据系统(C-TIRADS)分类间差异均有统计学意义(P<0.05)。多因素logistic回归分析显示,与包膜接触是EFVPTC颈部淋巴结转移的独立危险因素(P<0.05);与包膜接触、最大径(>10 mm)和年龄<55岁是IEFVPTC颈部淋巴结转移的独立危险因素(P<0.05)。结论FVPTC与CPTC间的特征差异主要是由于EFVPTC与CPTC的差异,EFVPTC更容易表现出良性特征。两亚组FVPTC在颈部淋巴结转移上有明显差异。Objective To investigate the ultrasonic and clinical features of two subtypes of follicular variant papillary thyroid carcinoma(FVPTC)and their correlation with cervical lymph node metastasis.Methods A total of 82 cases of FVPTC confirmed by pathology were analyzed retrospectively,including 31 cases of encapsulated group(EFVPTC)and 51 cases of invasive encapsulated group(IEFVPTC).To analyze their ultrasonic and clinicopathological features and further to explore their correlation with cervical lymph node metastasis in FVPTC groups.Results There were statistically significant differences in maximum diameter,blood flow signal and cervical lymph node metastasis between IEFVPTC and EFVPTC groups;The differences of FVPTC and CPTC(classic papillary thyroid carcinoma)in rich blood flow,very low echo and C-TIRADS classification were also statistically significant(P0.05).Multivariate logistic regression analysis showed that signs of contact with capsule was an independent risk factor for cervical lymph node metastasis for EFVPTC(P0.05);While for IEFVPTC,signs of contact with the capsule,size 10 mm and age 55 were independent factors for metastasis(P0.05).Conclusions The difference between FVPTC and CPTC is mainly due to the difference between EFVPTC and CPTC.EFVPTC is more likely to show benign signs.The two subtypes of FVPTC have significant differences in cervical lymph node metastasis.

关 键 词：滤泡型甲状腺乳头状癌 超声 甲状腺超声影像报告和数据系统 颈部淋巴结 

分 类 号：R736.1[医药卫生—肿瘤] R445.1[医药卫生—临床医学]