腹盆部原发孤立性纤维瘤的影像表现与病理对照  

Imaging and pathological features of primary solitary fibrous tumors in abdomen and pelvis

作　　者：薛良圆 徐磊 郭晓霖 田春梅[3] 张林[1] XUE Liangyuan;XU Lei;GUO Xiaolin;TIAN Chunmei;ZHANG Lin(Department of Radiology,Binzhou Medical University Hospital,Binzhou 256603,China;Department of Pathology,Binzhou Medical University Hospital,Binzhou 256603,China;Department of Pediatrics,Binzhou Medical University Hospital,Binzhou 256603,China)

机构地区：[1]滨州医学院附属医院放射科,山东滨州256603 [2]滨州医学院附属医院病理科,山东滨州256603 [3]滨州医学院附属医院儿科,山东滨州256603

出　　处：《分子影像学杂志》2023年第5期863-867,共5页Journal of Molecular Imaging

基　　金：滨州医学院研究生教学案例库建设项目(BYYJSALK2021007)。

摘　　要：目的对照病理分析腹盆部原发孤立性纤维瘤(SFT)的影像特征表现。方法回顾性分析12例经病理证实为腹盆部SFT患者的影像资料,其中4例行CT检查,2例行MRI检查,6例同时行CT及MRI检查,并与病理结果进行对照分析。结果SFT发生于腹腔4例,盆腔5例,腹股沟区1例,同时位于腹盆腔2例。肿块呈囊实性1例、实性11例,最大径6.3~20.0 cm。CT平扫肿块呈等/低密度,病灶内见钙化灶3例,出血灶1例。MRI平扫T1WI呈等低信号8例,T2WI/T2压脂呈均匀低信号1例,余7例均呈高低混杂信号,特征“阴阳图”4例,瘤内见流空血管影4例。增强扫描:12例均呈不均匀强化,10例呈“地图样”强化,2例呈花斑样强化,其中1例呈持续强化,1例呈渐进性强化,其余10例呈“快进慢出型”强化;6例瘤内见迂曲血管影,即“蚯蚓钻土”征。除坏死囊变区外,将8例行MRI检查的肿瘤实性成分分为两类:A类结节,T1WI等信号,T2WI/T2压脂低信号,增强检查无强化;B类结节,T1WI等低信号,T2WI/T2压脂高信号,增强检查呈轻-中度/显著强化,5例肿块为两类结节共存,3例为B类结节。病理示:5例肿瘤细胞见异型性及核分裂像增多,为非典型或恶性SFT。12例SFT的免疫组化标记物中,CD34阳性率100%,STAT6及Bcl-2阳性率91.7%,Vimentin阳性率83.3%,CD99阳性率75%。结论腹盆部SFT存在特征性影像表现,且肿块内部不同影像特征与病理组织成分相对应。肿块直径>10 cm或瘤内出现不规则钙化灶时,应警惕肿瘤恶变可能。结合免疫组化标记物对该疾病的诊断及鉴别诊断具有重要意义。Objective To analyze the imaging features of primary solitary fibrous tumors(SFT)in the abdomen and pelvis,according to the pathology.Methods We retrospectively analyzed the imaging data of 12 cases with pathologically confirmed abdominal and pelvic SFT,4 cases underwent CT examination,and 2 cases underwent MRI examination.6 cases underwent CT and MRI examination at the same time,and the pathological results were compared with the analysis of the pathological results.Results On plain CT scan,the mass showed equal/low density.There were 3 cases of calcification and 1 case of hemorrhage.On MRI plain scan,8 cases showed isohypotension on T1WI,1 case showed uniform hypotension on T2WI/T2 lipid pressure,the other 7 cases showed high and low mixed signals,4 cases showed"Yin-Yang"pattern,4 cases showed flow empty vessels in tumor.Enhanced scanning:12 cases were inhomogeneous enhancement,10 cases were"map like"enhancement,2 cases were piebald like enhancement,of which 1 case was continuous enhancement,1 case was gradual enhancement,and the remaining 10 cases were"fast in and slow out"enhancement.Tortuous blood vessels were seen in the tumors in 6 cases,namely"earthworm digging into the earth"sign.Except for necrotic cystic areas,the solid components of the tumor examined by MRI were divided into two categories:Type A nodules,T1WI isointense,T2WI/T2 hypopolipid signal,no enhancement on enhanced examination;Type B nodules,low signal intensity on T1WI and high signal intensity on T2WI/T2 lipid pressure,showed mild to moderate/significant enhancement on enhanced examination.5 cases of mass were 2 types of nodules coexisting,and 3 cases were type B nodules.Pathology showed that 5 cases of tumor cells showed atypical or malignant SFT.The positive rate of CD34 was 100%,STAT6 and Bcl-2 were 91.7%,Vimentin was 83.3%,and CD99 was 75%.Conclusion There are characteristic imaging features in abdominal and pelvic SFT,and different imaging features in the mass correspond to the pathological tissue components.When the diameter of the ma

关 键 词：孤立性纤维瘤 腹盆部 磁共振成像 计算机体层成像 病理学 

分 类 号：R738.6[医药卫生—肿瘤] R445.2[医药卫生—临床医学]