以颞颌关节炎为首发表现的IgD型多发性骨髓瘤一例  

Temporomandibular arthritis as the initial symptom of IgD multiple myeloma:a case report

作　　者：张慧敏[1] 谢丽娜 刘雪乐 赵丹[1] 刘清池[1] Zhang Huimin;Xie Lina;Liu Xuele;Zhao Dan;Liu Qingchi(Department of Hematology,the First Hospital of Hebei Medical University,Shijiazhuang 050030,China;不详)

机构地区：[1]河北医科大学第一医院血液内科,石家庄050030 [2]深州市医院功能科,衡水053800

出　　处：《新医学》2023年第10期764-768,共5页Journal of New Medicine

摘　　要：多发性骨髓瘤(MM)是一种恶性浆细胞病,以骨痛、肾功能不全、贫血、高钙血症为主要症状,临床表现复杂多样,极易误诊、漏诊。以颞颌关节炎为首发表现的MM少见,该文报道1例以颞颌关节炎为首发表现的IgD型MM 48岁男性患者,其以右侧颞颌关节区疼痛、麻木为首发症状,曾就诊于多个科室,影像学检查怀疑为MM,最终经骨髓穿刺、免疫固定电泳等确诊。该例提示临床医师应提高对MM的认识水平,尤其是诊断相对困难的IgD型MM,以减少误诊和漏诊。Multiple myeloma(MM)is a malignant plasma cell disease with bone pain,renal insufficiency,anemia and hypercalcemia as the main symptoms.It is likely to be misdiagnosed and missed diagnosis because of complex clinical manifestations.MM with temporomandibular arthritis as the initial symptom is rare.In this article,the diagnosis and treatment of one case of IgD MM with temporomandibular arthritis as the initial symptom were reported.The 48-year-old male patient presented with pain and numbness in the right temporomandibular area as the initial symptoms.He was admitted to different local hospitals.Imaging examination was highly indicative of MM,which was eventually confirmed by bone marrow aspiration and immunofixation electrophoresis.This case prompts that clinicians should deepen the understanding of MM,especially IgD MM that is relatively difficult to diagnose,aiming to lower the risk of misdiagnosis and missed diagnosis.

关 键 词：多发性骨髓瘤 IgD型 颞颌关节 关节炎 

分 类 号：R733.3[医药卫生—肿瘤]