SFCT对视网膜分支静脉阻塞并发黄斑水肿患者预后相关性的分析  

Prognostic relevance of SFCT for patients with macular edema caused by branch retinal vein occlusion

作　　者：尔若男 凌佼佼 陆璐 余锦强[2] ER Ruonan;LING Jiaojiao;LU Lu;YU Jinqiang(Postgraduate Training Base,Jinzhou Medical University,Hubei University of Medicine,Shiyan,Hubei 442000,China;Department of Ophthalmology,Shiyan Renmin Hostipal,Shiyan,Hubei 442000,China)

机构地区：[1]锦州医科大学湖北医药学院研究生培养基地,湖北十堰442000 [2]湖北省十堰市人民医院眼科,湖北十堰442000

出　　处：《中国医学工程》2023年第10期24-28,共5页China Medical Engineering

摘　　要：目的分析视网膜分支静脉阻塞(BRVO)并发黄斑水肿(ME)患者的脉络膜厚度的变化,探讨脉络膜厚度变化与患者预后的相关性。方法选取2022年1月至2023年1月于湖北省十堰市人民医院就诊的单眼视网膜分支静脉阻塞并发黄斑水肿的患者47例47眼。其中男22例22眼,女25例25眼,年龄44~65岁,平均(52.47±5.63)岁,发病时间不超过3个月。采用自身对照设计回顾性分析,记录患眼治疗前和治疗后1个月,3个月,6个月的最佳矫正视力(BCVA)、黄斑中心凹下脉络膜厚度(SFCT)以及视网膜中心凹厚度(CMT)。分析SFCT及CMT与BCVA的相关性及变化趋势,观察并记录治疗后1个月内并发症发生情况。结果患者年龄与视力预后无相关性(P>0.05);患眼不同时间点LogMAR BCVA、SFCT、CMT在治疗前后总体差异有统计学意义(P<0.05);患眼治疗前后SFCT、CMT与视力预后呈负相关(P<0.05)。患眼SFCT治疗后呈下降趋势(P<0.05);患眼CMT治疗后呈下降趋势(P<0.05);治疗过程中,无任何患者出现高眼压、眼内炎、玻璃体积血等严重并发症。结论治疗前BRVO-ME患者SFCT及CMT高于对侧健眼,治疗后呈下降趋势。患眼SFCT与视力呈负相关,治疗后SFCT降低,且降低程度越高,视力预后越好。患眼CMT与视力呈负相关,治疗后CMT降低,且降低程度越高,视力预后越好。对于BRVO-ME患者,玻璃体腔抗血管内皮生长因子(VEGF)药物联合无灌注区视网膜激光光凝治疗可有效降低CMT及SFCT,提高患者视力。【Objective】To discuss the changes of choroidal thickness in patients with macular edema caused by branch retinal vein occlusion(BRVO)and investigate the relationship between choroidal thickness changes and patients'prognosis.【Methods】From January 2022 to January 2023,47 patients with macular edema secondary to BRVO(BRVO-ME)in single eye treated in Shiyan People's Hospital in Hubei Province were chosen.They were aged from 44 to 65 years old,with a mean age of 52.47±5.63 years,and also the development of the disease did not last more than three months.Among them,22 cases and 22 eyes were male and 25 cases and 25 eyes were female.The best corrected visual acuity(BCVA),subfoveal choroidal thickness(SFCT),and central macular thickness(CMT)were recorded before and 1,3,and 6 months after treatment using a retrospective analysis with a self-control design.These all were used as the observation index.The correlation and trend of SFCT and CMT with BCVA were analyzed.the occurrence of complications within 1 month after treatment was observed and recorded.【Results】There was no correlation between patients age and visual prognosis(P>0.05).The overall differences in LogMAR BCVA,SFCT,and CMT at different time points in the affected eyes were statistically significant before and after treatment(P<0.05).SFCT and CMT were negatively correlated with visual prognosis before and after treatment(P<0.05).The SFCT of the affected eye showed a decreasing trend after treatment(P<0.05);the CMT of the affected eye showed a decreasing trend after treatment(P<0.05).No patient developed serious complications such as high intraocular pressure,endophthalmitis,and vitreous hemorrhage during the treatment.【Conclusion】The SFCT and CMT of BRVO-ME patients were higher than those of the contralateral healthy eyes before treatment,and showed a decreasing trend after treatment.The SFCT of the BRVO-ME patients was negatively correlated with the visual acuity.The SFCT decreased after treatment,and the higher the decrease,the better the pr

关 键 词：视网膜分支静脉阻塞 黄斑水肿 脉络膜厚度 视网膜中心凹厚度 

分 类 号：R774.1[医药卫生—眼科]