主观认知下降的研究进展  

Research Progress of Subjective Cognitive Decline

作　　者：李世平 王越[1,2] 郑华光 LI Shiping;WANG Yue;ZHENG Huaguang(Department of Neurology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China;China National Clinical Research Center for Neurological Diseases,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)

机构地区：[1]首都医科大学附属北京天坛医院神经病学中心,北京100070 [2]国家神经系统临床医学疾病研究中心

出　　处：《中国卒中杂志》2023年第10期1101-1114,共14页Chinese Journal of Stroke

基　　金：中国科学院战略性先导科技专项(XDB39040200)。

摘　　要：主观认知下降指患者出现自我感觉认知下降但客观认知检测无异常,是最近研究的热点。近年来,关于主观认知下降的发病率、危险因素、干预治疗等方面的研究逐渐增多。本文汇总了国内外相关文献,对主观认知下降的特点进行综述,包括主观认知下降的定义、流行病学特征、病因、临床评估、鉴别诊断及干预治疗等,旨在探讨主观认知下降的临床意义,为后续临床研究提供参考。Subjective cognitive decline(SCD)is a recent research hotspot,which refers to patients with self-perceived cognitive decline but no abnormality in objective assessment.Recently,there have been increasing studies on the incidence,risk factors,and intervention treatment of SCD.This paper summarizes the relevant studies at home and abroad to review the characteristics of SCD,including the definition,epidemiological characteristics,etiology,clinical evaluation,differential diagnosis,and intervention.The objective is to explore the clinical significance of SCD and to provide information for subsequent clinical research.

关 键 词：主观认知下降 阿尔茨海默病 轻度认知障碍 

分 类 号：R749.16[医药卫生—神经病学与精神病学]