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作 者:Jeongduk Seo Joonpyo Lee Yong Hoon Shin Albert Youngwoo Jang Soon Yong Suh
机构地区:[1]Department of Cardiology,Gachon University Gil Medical Center,Incheon 405-760,South Korea
出 处:《World Journal of Clinical Cases》2023年第30期7497-7501,共5页世界临床病例杂志
摘 要:BACKGROUND Protein C deficiency is typically associated with venous thromboembolism;however,arterial thrombosis has been reported in several cases.We report the case of a patient with pulmonary thromboembolism and deep vein thrombosis following acute myocardial infarction with high thrombus burden.CASE SUMMARY A 40-year-old man was diagnosed with pulmonary thromboembolism and deep vein thrombosis without any provoking factors.The patient was treated with anticoagulants for six months,which were then discontinued.Three months after the discontinuation of anticoagulant therapy,the patient was hospitalized with chest pain and diagnosed with acute myocardial infarction with high thrombus burden.Additional tests revealed protein C deficiency associated with thrombophilia.The patient was treated with anticoagulants combined with dual antiplatelet agents for 1 year after percutaneous coronary intervention,and no recurrent events were reported during a follow-up period of 5 years.CONCLUSION Recurrent thromboembolic events including acute myocardial infarction with thrombus should be considered an alarming sign of thrombophilia.
关 键 词:Venous thromboembolism THROMBOPHILIA Protein C deficiency ST elevation myocardial infarction ANTICOAGULATION Case report
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