电化学生物传感在HIV检测中的应用进展  

Application of electrochemical biosensing in HIV detection:a progress review

作　　者：邓培雪 叶力 陈荣凤 安三奇 蒋俊俊 梁浩 DENG Peixue;YE Li;CHEN Rongfeng;AN Sanqi;JIANG Junjun;LIANG Hao(Institute of Life Sciences,Guangxi Medical University,Nanning 530021,China;Guangxi Zhuang Autonomous Region Key Laboratory of AIDS Prevention and Control,Nanning 530021,China)

机构地区：[1]广西医科大学生命科学研究院,南宁530021 [2]广西艾滋病防治研究重点实验室,南宁530021

出　　处：《中国公共卫生》2023年第7期924-929,共6页Chinese Journal of Public Health

基　　金：广西科技计划资助项目(桂科AD21220013);国家重点研发计划子课题(2022YFC2305001)。

摘　　要：电化学生物传感器具有小型化、低成本、灵敏度高、检测快速、检测限低等优点,在HIV病毒检测领域受到广泛关注。本文综述了电化学生物传感技术用于HIV核酸或抗原检测的研究进展,并与传统检测方法进行对比,分析电化学生物传感检测的优劣势。Electrochemical biosensors have advantages of miniaturization,low cost,high sensitivity,rapid detection and low detection limit,and have attracted extensive attention in the field of human immunodeficiency virus(HIV)detection.This paper reviews research progress in electrochemical biosensor technology for HIV nucleic acid or antigen detection,compares it with routine detection methods,and analyzes the advantages and disadvantages of electrochemical biosensor detection.

关 键 词：HIV 电化学生物传感检测 核酸 HIVp24 GP120 

分 类 号：R512.91[医药卫生—内科学] TP212.3[医药卫生—临床医学]