supported by grants from the Natural Science Foundation of China(82072276 and 81772194 to ST,82073898 and 31370781 to SL,and 81630090 to SJ).
Apart from mediating viral entry,the function of the free HIV-1 envelope protein(gp120)has yet to be elucidated.Our group previously showed that EP2 derived from oneβ-strand in gp120 can form amyloid fibrils that inc...
National Natural Science Foundation Project(No.81960303);Baise City Scientific Research and Technology Development Plan Project(No.Encyclopedia 20213301,Encyclopedia 20213242,Encyclopedia 20194701);Guangxi Health Commission self funded research project(No.Z20190202,Z20211114);Guangxi University Young and Middle School Teachers'Basic Research Ability Enhancement Project(No.2021KY0538);2022 Traditional Chinese Medicine Self funded Research Project(No.GXZYL20220304);Open Project of Guangxi Key Laboratory of Molecular Pathology of Hepatobiliary Diseases(No.GXZDSYS-009)。
Objective:To investigate the effects of exosomes from human T lymphocyte line(H9)treated with HIV envelope protein gp120 on macrophage polarization.Methods:The viability of gp120-treated H9 T lymphocytes was as-sessed...
The current work was supported by the National Natural Science Foundation of China(No.81502675).
Even the potential of T cell-mimicking nanotrap for long term viral control due to its overcoming of human immunodeficiency virus(HIV)genetic diversity and viral resistance,the robust HIV inhibition was not expected b...