安徽省成年居民平均盐摄入量3种随机点尿计算方法与24 h尿钠法估算比较  

Comparison of three random spot urine-based calculations with 24-hour urine sodium measurement for mean salt intake estimation:a sampling study in adult residents of Anhui province

作　　者：徐伟[1] 邢秀雅[1] 许精巧 吕逸丽 程倩瑶 陈叶纪[1] 王华东[1] 刘志荣[1] XU Wei;XING Xiuya;XU Jingqiao;LÜYili;CHENG Qianyao;CHEN Yeji;WANG Huadong;LIU Zhirong(Public Health Research Institute of Anhui Province,Anhui Provincial Center for Disease Control and Prevention,Heifei 230601,China)

机构地区：[1]安徽省疾病预防控制中心(安徽省公共卫生研究院),合肥230601

出　　处：《中国公共卫生》2023年第8期1007-1012,共6页Chinese Journal of Public Health

摘　　要：目的比较3种随机点尿计算方法与24 h尿钠法估算安徽省成年居民平均盐摄入量的差异和一致性,为验证3种随机点尿方法估算人群盐摄入量方法的可靠性提供参考依据。方法收集2019年安徽省成年居民高血压和钠摄入量监测基线调查中随机尿样合格3329人、24 h尿样合格1500人以及24 h尿样和随机尿样配对1493人的相关数据,采用3种点尿转换24 h尿钠方法估计平均盐摄入量,并与24 h尿钠法估算的盐摄入量进行比较;应用配对样本t检验、组类内相关系数(ICC)分析和Bland-Altman图检验3种随机点尿计算方法与24 h尿钠法的差异和一致性。结果基于24 h尿钠法估算的安徽省成年居民平均盐摄入量为9.1(95%CI=8.9~9.4)g/d,Kawasaki、Tanaka和INTERSALT 3种随机点尿计算方法估算的安徽省成年居民平均盐摄入量分别为12.7(95%CI=12.6~12.9)、9.5(95%CI=9.4~9.6)和8.6(95%CI=8.5~8.7)g/d。配对比较结果显示,Tanaka随机点尿计算方法估算的结果最接近24 h尿钠法,平均差值为0.2(95%CI=0.0~0.4)g/d;Tanaka随机点尿计算方法估算的ICC值最高(0.34),INTERSALT随机点尿计算方法估算的ICC值次之(0.33),Kawasaki随机点尿计算方法估算的ICC值最低(0.23);3种点尿法的估计值与24 h尿钠法的估计值吻合较好,除Kawasaki外,INTERSALT和Tanaka随机点尿计算方法估算的结果在低水平盐摄入量时可能高估,在高水平摄入时可能低估。结论安徽省成年居民盐摄入量的3种点尿估计方法均与24 h尿钠法一致,Tanaka法相对更准确地估计人群盐摄入量。Objective To compare disparities between three random spot urine-based calculations and 24-hour urine sodium measurement in mean salt intake estimation among adult residents in Anhui province for evaluating the reliability of the three spot urine-based mean salt intake estimation methods.Methods Random spot and 24-hour urine samples were collected from permanent adult residents(18–69 years old)participating in a hypertension and sodium intake baseline survey during 2018 in Anhui province.The eligible samples included spot urine samples from 3329 participants and 24-hour urine samples from 1500 participants,of which 1493 had both spot and 24-hour urine samples.Mean salt intake of the participants was estimated according to determination of spot urine samples using the three(INTERSALT/Kawasaki/Tanaka)equations and the calculated results were compared with the measurement from 24-hour urine samples.Differences between the mean salt intake estimations based on spot urine samples and 24-hour urine samples were examined with paired t-test,intraclass correlation coefficient(ICC)analysis,and Bland-Altman plot test.Results The mean salt intake based on 24-hour urine measurement was 9.1 g/day(95%confidence interval[CI]:8.9–9.4);the spot urine-based mean salt intakes(in g/day)calculated using INTERSALT,Kawasaki,and Tanaka equation were 8.6(95%CI:8.5–8.7),12.7(95%CI:12.6–12.9),and 9.5(95%CI:9.4–9.6),respectively.The paired comparison showed that the estimation derived from Tanaka equation was the closest to the 24-hour urine-based measurement,with a difference of 0.2 g/d(95%CI:0.0–0.4).Among the three equations,the ICC was the highest(0.34)for Tanaka,followed by that of INTERSALT(0.33)and Kawasaki(0.23).The three spot urine-based estimations of mean salt intake were in good agreement with that of 24-hour urine-based measurement;while the estimations derived from INTERSALT and Tanaka equation could be higher under the condition of lower level salt intake but lower under the condition of higher level salt intake.Co

关 键 词：平均盐摄入量 24 h尿钠法 随机点尿计算方法 比较 成年居民 

分 类 号：R151.42[医药卫生—营养与食品卫生学]