HPV相关口咽癌诊疗现状及治疗研究进展  

Research progress in diagnosis and treatment of HPV-associated oropharyngeal squamous cell carcinoma

作　　者：何美霖 易俊林[1] HE Meilin;YI Junlin(Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,100021,China)

机构地区：[1]国家癌症中心,肿瘤临床研究中心,北京协和医学院中国医学科学院肿瘤医院放疗科,北京100021

出　　处：《临床耳鼻咽喉头颈外科杂志》2023年第9期734-739,共6页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：口咽癌是常见的头颈部恶性肿瘤之一。近年来,人乳头状瘤病毒相关性口咽鳞状细胞癌(human papilloma virus-associated oropharyngeal squamous cell carcinoma,HPV-OPSCC)发病率呈逐年上升趋势。随着外科微创手术技术的进步、调强放射治疗的广泛应用,以及患者对器官功能保护和更高生活质量的需求,HPV-OPSCC独特的生物学行为和较好的预后引发了一系列减毒治疗模式的探索。现结合相关报道就口咽癌诊疗现状及相关研究进展做一综述。Oropharyngeal carcinoma is one of the most common malignant tumors of head and neck.In recent years,the incidence of Human papilloma virus-associated oropharyngeal squamous cell carcinoma(HPV-OPSCC) has been increasing year by year.With the advancement of minimally invasive surgical techniques,the wide application of intensity modulated radiation therapy,and the demand of patients for organ function protection and higher quality of life,the unique biological behavior and better prognosis of HPV-OPSCC have led to the exploration of a series of attenuated treatment modes.This article reviews the diagnosis and treatment status of oropharyngeal cancer and related research progress based on relevant reports.

关 键 词：口咽肿瘤 人乳头状瘤病毒相关口咽肿瘤 诊断 治疗策略 预后 

分 类 号：R739.8[医药卫生—肿瘤]