腹腔5-氟尿嘧啶缓释剂包裹植入物的CT表现  

CT findings of sustained-release 5-fluorouracil enwrapped implants in abdominal cavity

作　　者：张瑜 刘会佳[1] 金晨望 张劲松[1] 宦怡 郑敏文 唐永强 ZHANG Yu;LIU Huijia;JIN Chenwang;ZHANG Jinsong;HUAN Yi;ZHENG Minwen;TANG Yongqiang(Department of Radiology,Xijing Hospital,the Air Force Medical University,Xi'an 710032,China;Department of Radiology,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)

机构地区：[1]空军军医大学西京医院放射科,陕西西安710032 [2]西安交通大学第一附属医院放射科,陕西西安710061

出　　处：《实用放射学杂志》2023年第9期1457-1461,共5页Journal of Practical Radiology

摘　　要：目的 探讨腹腔 5-氟尿嘧啶缓释剂包裹植入物(5-FUEI)的 CT特征.方法 回顾性分析符合纳入和排除标准的 70 例消化系统恶性肿瘤患者的CT图像,观察 5-FUEI的位置、大小、形状、密度、边界、强化程度、邻近结构及随访变化.结果 CT共检出 120 处 5-FUEI,主要分布在肝脾周(65 处)、结肠旁(42 处)、小网膜囊(5 处)及腹膜反折区(8 处).5-FUEI长径 1.27~4.21 cm,平均(2.48±0.62)cm,短径 0.61~3.03 cm,平均(1.82±0.59)cm.按形状可分为梭形 28 处(23.3%),类圆形 92 处(76.7%).梭形 5-FUEI中 6 处(21.4%)呈"枣核状"改变,类圆形 5-FUEI中 60 处(65.2%)呈"同心圆"改变.所有 5-FUEI边界较清,边缘及内部呈轻度强化.邻近实质脏器或肠壁弧形强化,局部腹膜网膜略增厚,周围脂肪间隙可见渗出.随访发现 5-FUEI 位置相对固定,形状可有改变,逐渐缩小且密度增高,呈囊性-囊实性-实性-钙化趋势.结论 腹腔 5-FUEI 的 CT 表现多样,典型表现为"同心圆"和"枣核状",随访呈动态变化也值得关注.Objective To investigate the CT characteristics of sustained-release 5-fluorouracil enwrapped implants(5-FUEI)in abdominal cavity.Methods The CT imaging of 70 patients with digestive malignancies who met the inclusion and exclusion criteria were retrospectively analyzed,including the location,size,shape,density,boundary,enhancement degree,adjacent structure and change of 5-FUEI during follow-up.Results A total of 1205-FUEI were detected by CT scanning,they were mainly distributed around the liver or spleen(n=65),near the colon(n=42),in lesser omental sac(n=5)and peritoneal reflection(n=8).The long diam-eter of 5-FUEI was 1.27-4.21 cm,mean(2.48±0.62)cm and the short diameter was 0.61-3.03 cm,mean(1.82±0.59)cm.The 5-FUEI with fusiform shape was observed on 28(23.3%)subjects and six of them showed"jujube pit"sign(21.4%),while the 5-FUEI with quasi-circular shape was observed on 92(76.7%)subjects and sixty of them showed"concentric circle"sign(65.2%).All 5-FUEI had clear boundary,the edge and inner region exhibited mild enhanced.Adjacent solid organ or bowel wall exhibited arc enhancement,the peritoneal omentum was locally slightly thickened.Meanwhile,the exudation can be seen in the surrounding fat space.During follow-up,it was found that the position of 5-FUEI was relatively fixed,along with shape shrinking,density increasing and a development trend from cystic,cystic-solid,solid object to calcification.Conclusion The CT findings of abdominal 5-FUEI are various,the typical manifestations are"concentric circle"and"jujube pit"sign,dynamic changes during the follow-up also deserves attention.

关 键 词：恶性肿瘤 5-氟尿嘧啶缓释剂 植入物 计算机体层成像 

分 类 号：R735[医药卫生—肿瘤] R814.42[医药卫生—临床医学]