肾上腺边缘入路三层面后腹腔镜肾上腺手术的临床研究  

Clinical study on laparoscopic adrenalectomy via three-layered adrenal margin approach

作　　者：胡敏雄[1] 巫扬标 许骁 杨泽松[3] 蔡旺海 潘宏宏 陈松茂[3] 林灯 洪怀山[3] 洪运[3] 连扬鹏[4] 吴进锋[1] 朱庆国[1] 叶烈夫[1] HU Minciong;WU Yangbiao;XU Xiao;YANG Zesong;CAI Wanghai;PAN Honghong;CHEN Songmao;LIN Deng;HONG Huaishan;HONG Yun;LIAN Yangpeng;WU Jinfeng;ZHU Qingguo;YE Liefu(Department of Urology,Fujian Provincial Hospital,Shengli Clinical Medical College of Fujian Medical University,Fuzhou,350001,China;Graduate School of Fujian Medical University;Department of Urology,Fujian Provincial Hospital South Branch;Center for Information Management,Fujian Provincial Hospital)

机构地区：[1]福建医科大学省立临床医学院福建省立医院泌尿外科,福州350001 [2]福建医科大学研究生学院 [3]福建省立医院南院泌尿外科 [4]福建省立医院信息管理中心

出　　处：《临床泌尿外科杂志》2023年第9期650-655,共6页Journal of Clinical Urology

基　　金：福建医科大学启航基金项目资助(No:2021QH1283);福建省自然科学基金(No:2021J01398)。

摘　　要：目的:总结肾上腺边缘入路三层面后腹腔镜肾上腺手术在治疗全人群肾上腺疾病的临床疗效。方法:回顾性收集在福建省立医院施行肾上腺边缘入路三层面后腹腔镜肾上腺手术的302例患者的临床资料。手术步骤第一、第二层面与常规三层面技术相同,肾上腺边缘入路第三层面为肾周脂肪与肾上腺之间。按照2016—2017年、2018—2019年和2020—2022年进行分组,统计分析、比较3组间患者基本特征及围手术期数据。结果:所有患者均成功进行了后腹腔镜肾上腺手术,排除肿瘤大于6 cm的19例患者,本研究共纳入283患者,无中转开放手术,无非计划切除肾上腺。男119例,女164例;病变位于左侧173例,右侧110例。平均年龄为(44.84±12.22)岁,平均体重指数(BMI)为(23.82±3.23)kg/m^(2),平均肿瘤直径为(2.96±1.49)cm。3组间患者基本特征差异均无统计学意义(P>0.05)。2016—2017年组手术时间最长,2018—2019年组手术时间最短,平均手术时间为(98.26±36.95)min,3组间手术时间差异有统计学意义(P<0.05)。平均术中出血量为(22.48±27.06)mL,平均引流管留置时间为(2.69±1.05)d,术后平均住院天数为(3.62±1.43)d。围手术期并发症发生率为6%,各组间差异无统计学意义。结论:肾上腺边缘入路三层面后腹腔镜肾上腺手术安全、可行、并发症少,无非计划切除同侧肾上腺。该技术有望成为肾上腺外科疾病的手术方法之一。Objective:To provide a comprehensive summary of the clinical efficacy of laparoscopic adrenalecto-my via three-layered adrenal margin approach for the treatment of adrenal diseases in the general population.Methods:The clinical records of 302 patients who underwent laparoscopic adrenalectomy via three-layered adrenal margin approach were retrospectively examined.The first and second layers of surgical procedures are the same as the conventional three-layer techniques.The adrenal margin approach third layer was situated amidst the perirenal adipose tissue and adrenal gland.The patients were stratified into three groups based on the time periods of 2016—2017,2018—2019,and 2020—2022,and their demographic characteristics and perioperative data were sta-tistically analyzed and compared among these groups.Results:Retro-laparoscopic adrenal surgery was successfully performed on all patients,except of 19 patients due to tumor diameter>6 cm.A total of 283 patients were included in this study without any conversions to open surgery or unplanned excisions of the adrenal glands.Among the patients,119 were male and 164 were female,with an average age of(44.84±12.22)years old and BMI of(23.82±3.23)kg/m^(2).The lesions occurred on the left side in 173 cases and on the right side in 110 cases,with an average tumor diameter of(2.96±1.49)cm.There were no significant differences in basic characteristics observed among the three groups(P>0.05).The 2016—2017 group had the longest operation time,while the 2018—2019 group had the shortest.The average operation time was(98.26±36.95)minutes,and there was a statistically significant difference among the three groups(P<o.05).The mean intraoperative blood loss was(22.48±27.06)mL,the mean duration of drainage was(2.69±1.05)days,and the mean length of postoperative hospital stay was(3.62±1.43)days.The incidence rate of perioperative complications was 6%,with no significant differences observed among all groups(P>0.05).Conclusion:The laparoscopic adrenalectomy via threelayered

关 键 词：腹腔镜 后腹腔镜肾上腺切除术 肾上腺 肾上腺边缘入路三层面 三层面 

分 类 号：R736.6[医药卫生—肿瘤]