胃肠道黏膜保护临床专家共识(2021年,福州)  

Consensus of Clinical Experts on Gastrointestinal Mucosal Protection(2021,Fuzhou)

作　　者：中华医学会消化病学分会胃肠激素与黏膜屏障学组 李景南[2] 姜海行[3] 蔺蓉[4] 王春晖[5] 徐桂芳[6] 徐严[7] 张炳勇[8] Gastrointestinal Hormone and Mucosal Barrier Group,Chinese Society of Gastroenterology,Chinese Medical Association;LI Jingnan(不详;Department of Gastroenterology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730)

机构地区：[1]不详 [2]中国医学科学院北京协和医学院北京协和医院消化内科,100730 [3]广西医科大学第一附属医院消化内科 [4]华中科技大学同济医学院附属协和医院消化内科 [5]四川大学华西医院消化内科 [6]南京大学医学院附属鼓楼医院消化内科 [7]吉林大学中日联谊医院消化内科 [8]河南省人民医院消化内科

出　　处：《胃肠病学》2022年第11期665-679,共15页Chinese Journal of Gastroenterology

摘　　要：胃肠道黏膜覆盖全胃肠道,具有重要的生理学作用。黏膜屏障与损伤是消化道疾病的共同发病机制,但在黏膜屏障损伤的临床诊断、病因诊断、治疗策略、黏膜保护剂的规范使用等方面仍缺乏深入、系统的认识。本共识基于循证医学证据,在胃黏膜屏障与保护的概念、黏膜屏障的生理作用、胃肠道黏膜损伤与相关疾病的发生机制、黏膜保护剂的分类和合理应用方面达成共识,旨在为胃肠道黏膜保护的临床应用提供依据。The gastrointestinal mucosa covers the entire gastrointestinal tract.With important physiological functions,the injuries of mucosal barrier are the common pathogenic mechanism of gastrointestinal diseases.However,there still lacks in⁃depth and systematic understanding in the clinical diagnosis,etiological diagnosis,treatment strategies of mucosal barrier injuries,and the standardized use of mucosal protective agents.Based on medicine⁃based evidence,this consensus has reached an agreement on the concept of gastric mucosal barrier and protection,physiological functions of mucosal barrier,gastrointestinal mucosal injuries and related diseases,and the classification and application of mucosal protective agents.The consensus provides a significant reference for gastrointestinal mucosal protection in clinical practice.

关 键 词：胃肠道黏膜 黏膜损伤 黏膜屏障 黏膜保护剂 

分 类 号：R57[医药卫生—消化系统]