牙骨质-骨结构不良21例诊治分析  

Cemento-Osseous dysplasia:Diagnosis and treatment of 21 cases

作　　者：刘宪光 颜淑云 王旭霞[1] LIU Xianguang;YAN Shuyun;WANG Xuxia(Department of Oral and Maxillofacial Surgery,School and Hospital of Stomatology,Shandong University,Jinan 250012;Department of Stomatology,The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250001,China)

机构地区：[1]山东大学口腔医院口腔颌面外科,济南250012 [2]山东中医药大学第二附属医院口腔科,济南250001

出　　处：《口腔颌面外科杂志》2023年第5期330-335,共6页Journal of Oral and Maxillofacial Surgery

摘　　要：目的:探讨牙骨质-骨结构不良(cemento-osseous dysplasias,COD)的临床诊疗特点。方法:收集经手术治疗的21例COD患者的临床诊疗资料,对患者的临床表现(年龄、性别、部位、症状和体征等)、影像学特征、术中情况及预后等进行回顾性分析。结果:21例COD患者中,女性发病率高于男性,40~49岁为好发年龄,约占52.4%;52.4%的患者无临床症状,病变好发于下颌骨,骨质隆起、牙齿缺失为常见体征,占57.1%;38.5%的病变造成下颌管移位,均未出现下唇麻木,30.8%的病变造成邻近牙齿牙根吸收;影像学上,69.2%的病变以透射影为主,30.8%的病变以阻射影为主;手术治疗为该病的有效治疗手段,术后病变区均显示骨形成。结论:COD是一种少见的颌骨结构异常,女性患者发病率明显高于男性,下颌骨较上颌骨多见,多数患者无临床症状,部分可发生感染症状,手术切除病变有利于骨质重新形成,是治疗该病的有效手段。Objective:To investigate the clinical characteristics of cemento-osseous dysplasia(COD).Methods:The clinical diagnostic and treatment data of 21 patients with COD were collected.The clinical manifestations(age,gender,location,symptoms and signs),imaging characteristics,intraoperative conditions and prognosis were recorded and analyzed retrospectively.Results:Among the 21 cases,the incidence rate of female were higher than that of male,and 40-49 years old was the predilection age,accounting for 52.4%.52.4%of the patients had no clinical symptoms.The lesions mostly located in mandible.Cortical bone expansion and missing teeth were common signs,accounting for 57.1%.38.5%of the lesions caused mandibular canal displacement without lower lip numbness,and 30.8%of the lesions caused root resorption of the adjacent teeth.In radiological imaging,69.2%of the lesions were mainly transparent and 30.8%were mainly resistant.Surgical treatment was effective for the disease,and new bone formation is found in the lesion area after operation.Conclusion:COD is a rare structural disorder of jaw.The incidence rate in female patients is significantly higher than that of male.It has a predilection for the mandible.Most patients have no clinical symptoms,and some infections can occur.Surgical r esection is beneficial for bone regeneration.

关 键 词：牙骨质-骨结构不良 颌骨 骨化纤维瘤 回顾性分析 

分 类 号：R782[医药卫生—口腔医学]