超声引导下亚甲蓝染色及体表标记双定位辅助切除不可触及乳腺病变的应用效果  

Application effect of ultrasound-guided methylene blue staining and body surface marker double positioning assisted resection on non-palpable breast lesions

作　　者：洪慧 周进 林征 HONG Hui;ZHOU Jin;LIN Zheng(Department of Surgical Oncology,Shangrao People's Hospital,Jiangxi Province,Shangrao 334000,China)

机构地区：[1]江西省上饶市人民医院肿瘤外科,江西上饶334000

出　　处：《中国当代医药》2023年第29期87-91,共5页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(202312271)。

摘　　要：目的探讨超声引导下亚甲蓝染色及体表标记双定位辅助切除不可触及乳腺病变(NPBL)的应用效果。方法选取2022年1月至12月在上饶市人民医院接受手术治疗的90例NPBL患者作为研究对象,采用随机数字表法分为对照组与观察组,各45例。对照组接受超声引导下体表标志定位,观察组采用超声引导下亚甲蓝染色及体表标记双定位辅助。比较两组患者的相关手术指标(切口程度、手术时间、切缘阳性率、病理时间、术中出血量、住院费用),比较两组患者术前、术后7 d的疼痛程度[视觉模拟评分法(VAS)]、生活质量[健康调查简表(SF-36)]、心理状况[焦虑自评表(SAS)、抑郁自评表(SDS)];出院后随访6个月,记录随访期间并发症(皮肤瘀斑、血肿、气胸、切口感染等)发生率及复发率;随访结束时比较两组患者对乳腺美观的满意度。结果观察组切口长度短于对照组,手术时间短于对照组,术中出血量少于对照组,观察组住院费用高于对照组,差异有统计学意义(P<0.05);两组患者术后7 d的VAS评分、SAS评分、SDS评分均低于本组术前,且观察组低于对照组,差异有统计学意义(P<0.05);两组术后7 d的SF-36评分高于本组术前,且观察组高于对照组,差异有统计学意义(P<0.05);两组的各项并发症发生率、肿瘤复发率、乳腺美观满意度比较,差异无统计学意义(P>0.05)。结论超声引导下亚甲蓝染色及体表标记双定位辅助切除NPBL,可以便于找到病变部位予以切除,提高手术效率并减少创伤,有利于患者术后恢复,减少术后疼痛以免焦虑和抑郁情绪产生,提高术后患者的生活质量,具有较高的推广应用价值。Objective To investigate the application effect of ultrasound-guided methylene blue staining and body surface marker double positioning assisted resection on non-palpable breast lesions(NPBL).Methods A total of 90 patients with NPBL who received surgical treatment in Shangrao People's Hospital from January to December 2022 were selected as research subjects,and were divided into control group and observation group by the random number table method,with 45 cases in each group.The control group received ultrasound-guided body surface marker positioning,and the observation group received ultrasound-guided methylene blue staining and body surface marker double positioning.The relevant surgical indicators(incision degree,operation time,positive rate of incision margin,pathological time,intraoperative blood loss,hospitalization cost)of the two groups were compared.The pain degree(visual analogue scale[VAS]),quality of life(MOS 36-item short-form health survey[SF-36]),psychological status(self-rating anxiety scale[SAS],self-rating depression scale[SDS])of the two groups were compared before and 7 days after surgery.The incidence and recurrence rate of complications(skin ecchymosis,hematoma,pneumothorax,incision infection)were recorded during the follow-up for 6 months after discharge.At the end of follow-up,the satisfaction of patients with breast beauty was compared between the two groups.Results The incision length in observation group was shorter than that in control group,and the surgical time was shorter than that in control group,and the intraoperative blood loss was less compared with that in control group,and the hospitalization cost was more than that in control group,with statistical significance(P<0.05).VAS score,SAS score and SDS score of two groups 7 days after surgery were lower than those before surgery,and observation group was lower than control group,with statistical significance(P<0.05).The SF-36 score of the two groups at 7 days after surgery was higher than that before surgery,and the observation gr

关 键 词：超声引导 亚甲蓝染色定位 体表标记 不可触及乳腺病变 

分 类 号：R737.9[医药卫生—肿瘤]