入肝血流不同处理方式对肝癌手术患者的疗效及对其不良反应的影响  

Effects of Different Treatment of Blood Flow into the Liver on the Efficacy and Adverse Reactions of Patients Underwent Liver Cancer Surgery

作　　者：王迁 王征征 王珣 WANG Qian;WANG Zhengzheng;WANG Xun(Cancer Hospital Affiliated to Zhengzhou University,Zhengzhou,450003)

机构地区：[1]郑州大学附属肿瘤医院,河南省肿瘤医院,450003

出　　处：《实用癌症杂志》2023年第10期1682-1684,共3页The Practical Journal of Cancer

摘　　要：目的探讨入肝血流不同处理方式对肝癌手术患者的疗效及对其不良反应的影响。方法选取收治的104例PLC患者,根据术中控制出血方式分为2组。其中研究组69例,采用不阻断入肝血流治疗,而对照组者35例,则采用半肝血流阻断治疗,比较2组患者的临床疗效等差异。结果研究组的术中失血量、手术时间及住院时间均优于对照组(P<0.05);术后研究组肝功能相关指标均比对照组明显改善(P<0.05);术后研究组患者的I级并发症发生率比对照组高,而Ⅱ~Ⅳ级并发症发生率比对照组低(P<0.05)。结论不阻断入肝血流对行肝癌手术患者的疗效更为显著,不仅可加快患者的康复速度,同时还可避免过度损伤肝功能,并能降低术后并发症的等级,值得临床推广应用。Objective To investigate the efficacy of different management of blood flow into the liver on patients undergoing surgery for hepatocellular carcinoma and the effect on their adverse effects.Methods 104 PLC patients were selected to be the study subjects.The patients were divided into 2 groups according to the way of intraoperative bleeding control.Among them,69 patients(the study group)were treated with no blockade of blood flow into the liver,while 35 patients(the control group)were treated with hemihepatic flow blockade.Results Intraoperative blood loss,operative time and hospital stay were better in the study group than in the control group(P<0.05);The liver function-related indexes in study group improved after surgery compared with those in the control group(P<0.05);After surgery,the incidence of grade I complications in the study group was higher than that in the control group,while the incidence of grade II-IV complications was lower than that in the control group(P<0.05).Conclusion The efficacy of not blocking blood flow to the liver is more significant for patients undergoing hepatocellular carcinoma surgery,which can not only speed up the recovery of patients,but also avoid excessive damage to liver function and reduce the grade of postoperative complications,so it is worthy of clinical promotion.

关 键 词：原发性肝癌 半肝血流阻断 不阻断入肝血流 疗效 并发症 

分 类 号：R735.7[医药卫生—肿瘤]