光生物调节疗法治疗口腔黏膜病的相关机制  

Mechanism of Photobiomodulation Therapy in the Treatment of Oral Mucosal Diseases

作　　者：李儒 李泽慧 郑明和 钟良军[1,2] 丁佩惠 LI Ru;LI Zehui;ZHENG Minghe;ZHONG Liangjun;DING Peihui(Stomatology Center,Affiliated Hospital of Hangzhou Normal University,Hangzhou 310015,China;School of Stomatology,Hangzhou Normal University,Hangzhou 310015,China;Stomatology Hospital,School of Stomatology,Zhejiang University School of Medicine,Zhejiang Provincial Clinical Research Center for Oral Diseases,Hangzhou 310000,China)

机构地区：[1]杭州师范大学附属医院口腔医学中心,杭州310015 [2]杭州师范大学口腔医学院,杭州310015 [3]浙江大学医学院附属口腔医院,浙江大学口腔医学院浙江省口腔疾病临床医学研究中心,杭州310000

出　　处：《激光生物学报》2023年第5期403-413,共11页Acta Laser Biology Sinica

基　　金：浙江省口腔疾病临床医学研究中心项目(2022-KFKT-08)。

摘　　要：光生物调节疗法作为口腔黏膜病治疗的辅助手段发展迅速,它通过细胞吸收光子能量,产生光化学效应,从而调节各种各样的生物过程来达到治疗目的。本文就减少炎症、加速组织愈合、缓解疼痛以及光生物调节的双向剂量作用4个方面进行综述,并深入探讨了其作用机制,以便为临床医师应用光生物调节疗法治疗口腔黏膜病提供更好的临床决策和依据。Photobiomodulation(PBM)as an adjunct method for the treatment of oral mucosal diseases has developed rapidly.It is through the absorption of photon energy by cells,produce photochemical effects,and thus regulate a variety of biological processes to achieve therapeutic purposes.In this paper,the four aspects of reducing inflammation,accelerating tissue healing,relieving pain and bidirectional dose of PBM are reviewed,and the mechanism of their action is deeply discussed in order to provide clinicians with better clinical decision and basis for the treatment of oral mucosal diseases with PBM therapy.

关 键 词：光生物调节 治疗 口腔黏膜病 发色团 双相剂量反应 

分 类 号：R781.5[医药卫生—口腔医学]