Long-term efficacy and safety of YAG laser vitreolysis for vision degrading myodesopsia  

作　　者：Tie-Zhu Lin Cheng Shi Xing Yang Emmanuel Eric Pazo Yan-Nian Hui Li-Jun Shen 

机构地区：[1]Department of Ophthalmology,Zhejiang Provincial People’s Hospital,Hangzhou 310000,Zhejiang Province,China [2]He Eye Specialist Hospital,Shenyang 110034,Liaoning Province,China [3]Department of Ophthalmology,Eye Institute of PLA,Xijing Hospital,Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China

出　　处：《International Journal of Ophthalmology(English edition)》2023年第11期1800-1805,共6页国际眼科杂志（英文版）

基　　金：Supported in part by the Shenyang Young and Middle-aged Science and Technology Innovation Talent Support Program(No.RC210267).

摘　　要：AIM:To assess the long-term efficacy and safety of yttrium-aluminum garnet(YAG)laser vitreolysis for vision degrading myodesopsia(VDM)caused by posterior vitreous detachment(PVD).METHODS:This retrospective study reviewed VDM patients of PVD type undergoing YAG laser vitreolysis.The baseline demographic information,the patterns of floaters,the number of floaters,and the subjective improvement of floater sympotoms(ranging from 0 to 100%)from medical records were collected.Significant improvement was defined as a relief of floater symptoms of≥50%at the final visit.The long-term efficacy and safety of YAG laser vitreolysis were analyzed.The risk factors linked to significant improvement of floater symptoms were defined using univariate and multivariate logistic regression analyses.RESULTS:The final analysis included 221 patients with VDM.The mean age of patients was 61.08±7.74y,and the mean length of follow-up was 21.38±5.61mo.Totally 57.01%of patients experienced a significant improvement in their floater symptoms after YAG laser therapy,and none of them developed delayed retinal abnormalities such as retinal tears or detachments.Age(OR=1.049,95%CI=1.007-1.092,P=0.021)was identified as a significant risk factor for significant improvement in VDM.CONCLUSION:YAG laser vitreolysis is an effective and secure treatment for PVD-type VDM,and patients of advanced age are more likely to get favorable outcomes.

关 键 词：FLOATERS posterior vitreous detachment YAG laser vitreolysis risk factors vision degrading myodesopsia 

分 类 号：R779.6[医药卫生—眼科]