微型机器人及其联合干细胞移植技术的研究进展  

Research advances of microrobots plus stem cell transplantation

作　　者：皮艺林 宋红丽[2] Pi Yilin;Song Hongli(The First Central Clinical School,Tianjin Medical University,Tianjing 300192,China;Department of Organ Transplantation,Tianjin First Central Hospital Tianjin Key Laboratory of Organ Transplantation Tianjin Clinical Medical Research Center of Organ Transplantation,Tianjin 300192,China)

机构地区：[1]天津医科大学一中心临床学院,天津300192 [2]天津市第一中心医院器官移植科,天津市器官移植重点实验室,天津市器官移植临床医学研究中心,天津300192

出　　处：《中华器官移植杂志》2023年第9期562-567,共6页Chinese Journal of Organ Transplantation

基　　金：国家自然科学基金 (82070639)。

摘　　要：微型机器人可在体内被无线控制,使诊断和治疗的侵入性减到最小;其联合干细胞移植是实现靶向精准治疗最重要的应用之一。干细胞移植技术在治疗许多临床疾病中具有很大潜力,但在实际应用时,仍存在诸如细胞栓塞导致的肺栓塞和梗死、感染、靶向性差等问题。本文从微型机器人的起源、设计类型、驱动方式、材料以及成像系统等方面全面介绍了微型机器人及其联合干细胞移植技术在实际应用中的研究进展及应用结果,并对其未来发展方向进行了展望。Microrobot may be controlled wirelessly in a patient for minimizing the invasiveness of diagnosis and treatment.Microrobot plus stem cell transplantation(SCT)is ideal for offering targeted precision therapy.SCT has great potentials for many common diseases.However,clinical application of SCT still has several perplexing problems such as pulmonary embolism and infarction due to cell embolism,infection and poor targeting.This review summarized the latest researches and applications of microrobots plus SCT from the perspectives of origins,design types,driving modes,materials and imaging systems.It also provided an outlook on their future development trends.

关 键 词：机器人 干细胞移植 靶向 运输 

分 类 号：R457.7[医药卫生—治疗学] TP242[医药卫生—临床医学]