基于Cite Space的国内缺血性脑卒中与同型半胱氨酸研究热点和发展趋势的可视化分析  

Visualized analysis of research hotspots and development trends of domestic ischemic stroke and homocysteine in China based on Cite Space

作　　者：刘帅[1] 杨清燕 LIU Shuai;YANG Qingyan(Huacao Community Health Service Center,Minhang District of Shanghai,Shanghai 201107,China)

机构地区：[1]上海市闵行区华漕社区卫生服务中心,上海201107

出　　处：《老年医学研究》2023年第5期24-30,共7页Geriatrics Research

基　　金：上海市闵行区自然科学研究课题(2022MHZ082,基于家庭医生服务的缺血性脑卒中现患人群同型半胱氨酸现状调查及干预研究)。

摘　　要：目的探讨我国缺血性脑卒中与同型半胱氨酸相关研究的热点、进展及前沿。方法数据来源为中国知网网络出版总库(CNKI),检索缺血性脑卒中与同型半胱氨酸相关的北京大学图书馆中文核心期刊、南京大学中文社会科学引文索引来源期刊、中国科学引文数据库核心期刊文献,用Note Express建立数据,用WPS Excel对所得文献的发表年度、发文作者、载文期刊进行分析;用Cite Space软件分别对作者、机构、关键词进行可视化分析。结果合计共得到649篇文献,2018年之前各年度发文量总体呈上升趋势,并于2014年达到最高(60篇),2018—2021年4年间发文量有所下降,但仍维持在年均20篇以上。发文量最多的期刊是《中国老年学杂志》,共刊文105篇,占纳入文献总数的16.18%;张哲成、张静、谈晓牧、刘怀翔、许予明、刘建国是高频发文作者,作者间合作较少,共形成2个自然聚类;发文机构最多的是天津医科大学第二医院(11篇),不同团队间合作极少,合作较多的主要在天津医科大学第二医院、天津市第三中心医院、北京市潞河医院之间,北京大学第一医院、北京大学人民医院、中国医科大学附属第一医院之间。关键词聚类共形成11个聚类群,其热点关键词主要有危险因素、丁苯酞、预后、认知障碍、脑卒中、维生素、基因、半胱氨酸、血糖、中青年、研究现况等。关键词突现分析显示,“相关性”是突现强度最高的关键词,其他强度较高的关键词还有基因、复发、丁苯酞、认知功能、认知障碍等。该领域研究前沿在向丁苯酞、胱抑素C、相关性、认知功能、认知障碍、神经功能、高血压等方向转移。结论总体发展趋势上,缺血性脑卒中与同型半胱氨酸相关领域各项研究呈现厚积薄发的趋势。关于基因、维生素、预后、认知障碍、危险因素的研究贯穿始终,有望继续延续;在丁苯酞、血�Objective To explore the hot spots,progress and trend of the research on ischemic stroke and homocys⁃teine in China.Methods The data source was CNKI,the core Journals of Peking University,Nanjing University,Chi⁃nese Science Citation Database related to ischemic stroke and homocysteine were searched.The data were established with Note Express.The published years,authors,and journals of the obtained literature were analyzed with WPS Excel.Cite Space software was used to visualize and analyze the author,organization and keywords.Results A total of 649 articles were collected,and the total number of articles published in each year before 2018 showed an upward trend,and reached its peak in 2014(60 articles).The number of articles decreased during the four years from 2018 to 2021,but still main⁃tained an average of more than 20 articles per year.The journal with the largest number of articles published was the Chi⁃nese Journal of Gerontology,with a total of 105 articles,accounting for 16.18%of the total included articles.Zhang Zhecheng,Zhang Jing,Tan Xiaomu,Liu Huaixiang,Xu Yuming and Liu Jianguo were the authors of high-frequency arti⁃cles.There was less cooperation among authors,and two natural clusters were formed.The Second Hospital of Tianjin Medical University published the most papers(11 papers),and there was little cooperation between different teams.There was more cooperation between the Second Hospital of the Tianjin Medical University,the Third Central Hospital of Tianjin and the Luhe Hospital of Beijing,and more cooperation between the Peking University First Hospital,the People's Hospi⁃tal of Peking University and the first Affiliated Hospital of China Medical University.A total of 11 clusters were formed by keyword clustering,hot keywords include risk factors,butylphthalide,prognosis,cognitive impairment,stroke,vita⁃mins,genes,L-Cysteine,blood glucose,youth and middle-aged,research status,etc.Keyword emergence analysis showed that"correlation"was the keyword with the highest intensity of eme

关 键 词：缺血性脑卒中 同型半胱氨酸 可视化分析 Cite Space 

分 类 号：R743[医药卫生—神经病学与精神病学]