过渡金属催化不对称C—H硼化反应研究进展  

Recent Progress in Transition-Metal-Catalyzed Asymmetric C—H Borylation

作　　者：王文芳 Wang Wenfang(Gansu Provincial Biomass Function Composites Engineering Research Center,Key Laboratory for Utility of Environment-Friendly Composite Materials and Biomass in University of Gansu Province,Key Laboratory of Environment-Friendly Composite Materials of the State Ethnic Affairs Commission,College of Chemical Engineering,Northwest Minzu University,Lanzhou 730000)

机构地区：[1]西北民族大学化工学院、环境友好复合材料国家民委重点实验室、甘肃省高校环境友好复合材料及生物质利用重点实验室、甘肃省生物质功能复合材料工程研究中心,兰州730000

出　　处：《有机化学》2023年第9期3146-3166,共21页Chinese Journal of Organic Chemistry

基　　金：中央高校基本科研业务费(31920190079);西北民族大学科研(xbmuyjrc 201905)。

摘　　要：过渡金属催化不对称C—H硼化反应是构建手性有机硼化合物最为有效的策略之一, 具有原子和步骤经济性, 在合成化学、药物化学和材料学等领域受到广泛关注. 新型手性配体的设计与合成是过渡金属催化不对称C—H硼化反应成功的关键, 根据手性配体的设计和发展过程, 对近年来实现的过渡金属催化不对称C(sp^(2))—H和C(sp^(3))—H硼化反应的研究进展进行综述.Transition-metal-catalyzed asymmetric C—H borylation is one of the most powerful strategies for the construction of chiral organoborate compounds, which has attracted extensive attention in the fields of synthetic chemistry, medicinal chemistry and materials science due to its atom- and step-economy. The design and synthesis of novel chiral ligands are essential for the success of asymmetric C—H borylation. Based on the design and development of chiral ligands, the recent progress of transition-metal-catalyzed asymmetric C(sp^(2))—H and C(sp^(3))—H borylation reactions is summarized.

关 键 词：不对称C—H硼化 手性配体 过渡金属配合物 

分 类 号：O621.251[理学—有机化学]