早期食管癌及癌前病变内镜治疗后并发症发生的因素分析  

Analysis of Influencing Factors of Complications After Endoscopic Treatment of Early Esophageal Cancer and Precancerous Lesions

作　　者：荆芳芳 陈琛[1] JING Fangfang;CHEN Chen(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)

机构地区：[1]郑州大学第一附属医院,450000

出　　处：《实用癌症杂志》2023年第11期1855-1858,共4页The Practical Journal of Cancer

摘　　要：目的 探讨早期食管癌及癌前病变患者经内镜治疗后并发症发生的因素。方法 选取行内镜治疗的89例食管癌及癌前病变患者,统计其术后并发症的发生率。收集临床资料,先开展单因素分析,待获得有统计学差异的项目后纳入Logistic回归分析模型,获得早期食管癌与癌前病变患者经内镜治疗后并发症发生的主要影响因素。结果 89例经内镜治疗后的患者发生并发症的有24例,发生率为26.97%(24/89),其中肺不张占比45.83%(11/24),食管狭窄占比33.33%(8/24),延迟出血占比20.83%(5/24);单因素分析显示:年龄、性别、病变部位、家族史、合并其他疾病、饮酒史、吸烟史与早期食管癌及癌前病变患者经内镜治疗后并发症的发生无关(P>0.05);而手术时间、病灶长径、病变浸润深度与内镜治疗后并发症发生有关(P<0.05);多因素Logistic回归分析显示:手术时间长、病灶长径≥50 mm、病变浸润深度sm1为早期食管癌及癌前病变患者经内镜治疗后并发症发生的主要影响因素(P<0.05)。结论 早期食管癌与癌前病变患者经内镜治疗后并发症发生率较高,而影响并发症发生的因素具有多样性,如手术时间长、病灶长径≥50 mm、病变浸润深度sm1,临床需对上述影响因素予以高度重视,采取针对性治疗干预措施,以改善其预后。Objective To explore the factors leading to complications in patients with early esophageal cancer and precancerous lesions after endoscopic treatment.Methods 89 patients with esophageal cancer and precancerous lesions who underwent endoscopic treatment were selected,and the incidence of postoperative complications was calculated.Collect clinical data,conduct univariate analysis first,and incorporate statistical differences into the logistic regression analysis model to obtain the main influencing factors of complications in patients with early esophageal cancer and precancerous lesions after endoscopic treatment.Results Among the 89 patients who underwent endoscopic treatment,24 had complications,with an incidence rate of 26.97%(24/89).Among them,atelectasis accounted for 45.83%(11/24),esophageal stenosis accounted for 33.33%(8/24),and delayed bleeding accounted for 20.83%(5/24);Univariate analysis showed that age,gender,lesion location,family history,combined with other diseases,drinking history,smoking history were not related to the occurrence of complications in patients with early esophageal cancer and precancerous lesions after endoscopic treatment(P>0.05);The surgical time,lesion length,and depth of lesion infiltration are related to the occurrence of complications after endoscopic treatment(P<0.05);Multivariate logistic regression analysis showed that long surgical time,lesion length≥50 mm,and lesion infiltration depth sm1 were the main influencing factors for the occurrence of complications in patients with early esophageal cancer and precancerous lesions after endoscopic treatment(P<0.05).Conclusion Patients with early esophageal cancer and precancerous lesions have a higher incidence of complications after endoscopic treatment,and the factors that affect the occurrence of complications are diverse,such as long surgical time,lesion length≥50 mm,and lesion infiltration depth SM1.Clinical attention should be paid to these influencing factors and targeted treatment interventions should be taken to imp

关 键 词：食管癌 癌前病变 并发症 影响因素 

分 类 号：R735.1[医药卫生—肿瘤]