ALBI评分在重症急性胰腺炎患者中的应用价值  

Clinical value of the ALBI score in patients with severe acute pancreatitis

作　　者：雷婷[1] 石秀芳[1] 梁影[1] LEI Ting;SHI Xiufang;LIANG Ying(Center of Laboratory,Bozhou People′s Hospital,Bozhou,Anhui 236800,China)

机构地区：[1]安徽省亳州市人民医院检验中心,安徽亳州236800

出　　处：《检验医学与临床》2023年第21期3172-3174,3179,共4页Laboratory Medicine and Clinic

摘　　要：目的探讨血清清蛋白-胆红素(ALBI)评分在重症急性胰腺炎(SAP)患者中的应用价值。方法选取2021年10月至2022年9月亳州市人民医院诊治的31例SAP患者为重症组,另选取该院同期收治的34例轻度胰腺炎(AP)患者作为轻症组。检测并比较两组患者的全血红细胞分布宽度(RDW)、血清钙(Ca)、总胆红素(TBIL)、清蛋白(ALB)水平及ALBI评分情况;采用Pearson相关分析SAP患者ALBI评分与各观察指标的相关性;采用二元Logistic回归分析SAP的影响因素。结果重症组RDW[(42.55±5.37)fL]、ALBI评分[(-2.57±0.62)分]高于轻症组[(40.31±3.66)fL、(-3.03±0.36)分],而血清Ca[(2.13±0.25)mmol/L]、ALB[(39.65±6.80)g/L]低于轻症组[(2.24±0.18)mmol/L、(44.29±4.24)g/L],差异均有统计学意义(P<0.05)。SAP患者的ALBI评分与RDW呈正相关(r=0.598,P<0.05),与血清Ca、ALB呈负相关(r=-0.626、-0.977,P<0.05)。二元Logistic回归分析显示,ALBI评分是SAP的独立危险因素(P<0.05)。结论ALBI评分可作为一种快速检测手段用于SAP的早期识别和诊疗,具有重要的临床价值。Objective To investigate the clinical value of albumin-bilirubin(ALBI)score in patients with severe acute pancreatic pancreatitis(SAP).Methods Thirty-one SAP patients diagnosed and treated in Bozhou People′s Hospital from October 2021 to September 2022 were selected as the severe group,and 34 mild AP patients admitted to the hospital during the same period were selected as the mild group.The whole blood red blood cell distribution width(RDW),serum calcium(Ca),total bilirubin(TBIL),albumin(ALB)and ALBI score of the patients were detected and compared between the two groups.Pearson correlation was used to analyze the correlation between the ALBI scores of the SAP patients and the related observational indexes.The binary Logistic regression was used to analyze the influencing factors of SAP.Results The RDW[(42.55±5.37)fL]and ALBI score[(-2.57±0.62)points]in the severe group were higher than those in the mild group[(40.31±3.66)fL,(-3.03±0.36)points],and serum Ca[(2.13±0.25)mmol/L],ALB[(39.65±6.80)g/L]were lower than those in the mild group[(2.24±0.18)mmol/L,(44.29±4.24)g/L],the differences were statistically significant(P<0.05).The ALBI score of SAP patients was positively correlated with RDW(r=0.598,P<0.05),and negatively correlated with serum Ca,ALB(r=-0.626,-0.977,P<0.05).Binary Logistic regression analysis showed that ALBI score was an independent risk factor for SAP(P<0.05).Conclusion ALBI score can be used as a rapid detection method for the early identification and diagnosis of SAP,with significant clinical value.

关 键 词：ALBI评分 重症急性胰腺炎 全血红细胞分布宽度 血清钙 

分 类 号：R576[医药卫生—消化系统]