恶性肿瘤化疗患者中心静脉置管感染危险因素分析  

Risk factors of central venous catheterization infection in patients with malignant tumor undergoing chemotherapy

作　　者：王兰 黄少军 陈嘉莉 胡婷婷 朱陈聪 WNAG Lan;HUANG Shao-jun;CHEN Jia-li;HU Ting-ting;ZHU Chen-cong(Xiangyang Central Hospital,Affiliated Hospital of Hubei University of Arts and Sciences,Xiangyang,Hubei 44102l,China)

机构地区：[1]湖北文理学院附属医院(襄阳市中心医院)肿瘤科,湖北襄阳441021 [2]湖北文理学院附属医院(襄阳市中心医院)检验科,湖北襄阳441021 [3]湖北文理学院附属医院(襄阳市中心医院)感控办,湖北襄阳441021

出　　处：《中华医院感染学杂志》2023年第19期3029-3032,共4页Chinese Journal of Nosocomiology

基　　金：湖北省自然科学基金资助项目(WJ2019F091)。

摘　　要：目的分析恶性肿瘤化疗患者中心静脉置管感染发生的危险因素.方法回顾性收集2020年1月-2022年6月湖北文理学院附属医院收治的308例恶性肿瘤中心静脉置管化疗患者的临床资料,根据患者中心静脉置管感染情况分为感染组(32例)和未感染组(276例);归纳恶性肿瘤化疗患者中心静脉置管感染的危险因素.结果308例恶性肿瘤化疗患者中心静脉置管感染32例,感染率为10.39%;多因素Logistic分析结果显示,置管时间、静脉高营养、曾入住重症加强护理病房是恶性肿瘤化疗患者中心静脉置管感染的危险因素(P<0.05).结论恶性肿瘤化疗患者中心静脉置管感染与置管时间、静脉高营养、曾入住重症加强护理病房密切相关,针对上述因素预防恶性肿瘤化疗患者中心静脉置管感染发生的价值较高,可改善患者预后.OBJECTIVE To analyze the risk factors for central venous catheterization infection in patients undergoing chemotherapy for malignancy.METHODS The clinical data of 308 patients with central venous catheter chemotherapy for malignant tumors admitted to the Affiliated Hospital of Hubei University of Arts and Sciences from Jan.2020 to Jun.2022 were retrospectively collected,and the patients were divided into the infected group(32 cases)and the uninfected group(276 cases)according to the infection status of central venous catheter.The risk factors of central venous catheterization infection in patients with malignant tumor chemotherapy were summarized.RESULTS There were 32 cases of central venous catheterization infection in 308 patients undergoing chemotherapy for malignancy,with an infection rate of 10.39%.Multivariate Logistic analysis showed that catheterization time,intravenous hypernutrition,and previous admission to an intensive care unit were risk factors for central venous catheterization infections in patients undergoing chemotherapy for malignancy(P<O.05).CONCLUSION Central venous catheterization infections in patients undergoing chemotherapy for malignancy were strongly associated with catheterization time,intravenous hypernutrition,and previous admission to an intensive care unit.Targeting these factors was of high value in preventing the occurrence of central venous catheterization infections in patients undergoing chemotherapy for malignancy and might improve patient prognosis.

关 键 词：恶性肿瘤 化疗 中心静脉置管 感染 危险因素 

分 类 号：R730.6[医药卫生—肿瘤]