牙种植体表面氧化锆气凝胶涂层的制备  

Surface modification of zirconia dental implants with ZrO_(2)aerogels

作　　者：李涛[1] 邓宏燕[1] 田月明[1] LI Tao;DENG Hong-yan;TIAN Yue-ming(Department of Prosthodontics,Capital Medical University School of Stomatology,Beijing 100050,China)

机构地区：[1]首都医科大学口腔医学院修复科,北京100050

出　　处：《北京口腔医学》2023年第5期305-308,共4页Beijing Journal of Stomatology

基　　金：国家自然科学基金(81901047);北京市医管局青年人才培养计划“青苗”计划(QML20201502)。

摘　　要：目的通过溶胶凝胶法和旋涂工艺在氧化锆牙种植体表面制备ZrO_(2)气凝胶多孔涂层。方法制备ZrO_(2)溶胶液,分别在旋涂转速为400 r/min、800 r/min、1200 r/min、2000 r/min参数设置下利用旋涂机,在氧化锆基体表面制备ZrO_(2)气凝胶。扫描电子显微镜下观察种植体表面形貌的变化,使用Brunauer-Emmett-Teller法测定ZrO_(2)气凝胶的比表面积及其多孔特性。结果在旋涂转速较低时(400 r/min),ZrO_(2)气凝胶在基体表面形成纤维管状结构,随着旋涂转速的增大出现片状的气凝胶。当转速达到1200 r/min形成均匀的ZrO_(2)气凝胶多孔涂层。在转速达到2000 r/min时,基体表面几乎观察不到气凝胶。结论当旋涂转速1200 r/min时,可在氧化锆基底上制备出均匀的、具有高孔隙率、高比表面积的ZrO_(2)气凝胶涂层,为种植体表面构建载药释药涂层提供新思路。Objective To modify the surface of zirconia dental implant with a porous ZrO_(2)aerogels coating by using Sol-gel method and spin coating process.Methods ZrO_(2)binding buffer was prepared,and zirconia substrates were placed in the spin coater under the spin speed of 400 r/min,800 r/min,1200 r/min,and 2000 r/min respectively to acquire ZrO_(2)aerogels coatings.Surface topography of the zirconia substrates was examined using scanning electron microscopy(SEM)and the specific surface was measured by Brunauer-Emmett-Teller method.Results At low spin speed(400 r/min),ZrO_(2)aerogel formed a fiber-tubular structure on the substrate surface,and flaky aerogel appeared with the increase of spin speed.Uniform porous ZrO_(2)aerogels were obtained while the spin speed was 1200 r/min.Conclusions When the spin speed was 1200 r/min,ZrO_(2)aerogel coating with high porosity and high specific surface area was prepared on the zirconia substrate.

关 键 词：种植体 表面改性 二氧化锆 气凝胶 

分 类 号：R783.1[医药卫生—口腔医学]