可吸收口腔修复膜用于口腔内软组织浅层缺损修复的临床研究  

Clinical effect of the absorbable oral repair membrane on the superficial defect repair of oral soft tissue

作　　者：王淑萍 殷卫红[2] 宋铁砾[2] 陈志远[2] 袁鼎翔 刘静明 WANG Shu-ping;YIN Wei-hong;SONG Tie-li;CHEN Zhi-yuan;YUAN Ding-xiang;LIU Jing-ming(Department of Stomatology,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China)

机构地区：[1]首都医科大学附属北京世纪坛医院口腔科,北京100038 [2]首都医科大学附属北京同仁医院口腔科 [3]首都医科大学口腔医学院

出　　处：《北京口腔医学》2023年第5期318-320,共3页Beijing Journal of Stomatology

摘　　要：目的探讨胶原蛋白类可吸收口腔修复膜修复口腔内软组织浅层缺损的临床效果。方法共纳入口腔内软组织浅层缺损患者32例。缺损部位为唇部、舌、颊部、腭部、前庭沟及口底。随机将研究对象分配成实验组和对照组各16例进行非劣效性实验。实验组采用胶原蛋白类可吸收口腔修复膜,对照组采用脱细胞基质类口腔修复膜。分别在术后7天,术后1个月和术后3个月记录实验组和对照组的创面愈合率、瘢痕形成率以及有无过敏、排斥、炎症反应。结果实验组和对照组口腔修复膜在术后都发生吸收降解,创面不断缩小。术后3个月创面愈合完全,留有少量瘢痕。与对照组相比,实验组的创面愈合率较高,瘢痕形成率较低,差异有统计学意义。实验组和对照组都不引起过敏、排斥、炎症反应。结论胶原蛋白类可吸收口腔修复膜能够促进口腔内软组织浅层缺损更快地修复,并且在修复过程中不引起过敏、排斥、炎症反应,修复后的瘢痕小。Objective To investigate the effect and safety of the absorbable collagen membrane in the repair of the superficial defect of oral soft tissue.Methods Thirty-two patients with superficial defect of oral soft tissue were selected in this study.The patients were randomly divided into absorbable collagen membrane group and acellular derma matrix group.Wound healing rate and scar formation rate were analyzed and inflammatory reaction at 7 days,1 month,3 months after operation were observed.Results The oral repair membrane in both groups degraded after operation and the wound surface was shrinking.The wound healing rate in absorbable collagen membrane group was significantly higher than that in acellular derma matrix group and the scar formation rate was significantly lower.No allergic rejection and inflammatory reaction were observed in both groups.Conclusions Absorbable collagen membrane may have the potential to enhance the repair of superficial defect of oral soft tissue.

关 键 词：可吸收口腔修复膜 软组织浅层缺损 口腔 

分 类 号：R783.1[医药卫生—口腔医学]