原发性咽旁间隙肿瘤的临床特征分析  

Clinical characteristics analysis of primary parapharyngeal space tumors

作　　者：李瑞龙 黄新生[2] 王鹏[2] LI Rui-long;HUANG Xin-sheng;WANG Peng(Department of Otorhinolaryngology,Zhongshan Hospital(Xiamen Branch),Fudan University,Xiamen Clinical Research Center for Cancer Therapy,Xiamen 361015,Fujian,China;Department of Otorhinolaryngology,Head and Neck Surgery,Zhongshan Hospital,Fudan University,Shanghai 200032,China)

机构地区：[1]复旦大学附属中山医院厦门医院耳鼻咽喉科,厦门市恶性肿瘤综合治疗临床研究中心,厦门361015 [2]复旦大学附属中山医院耳鼻咽喉头颈外科,上海200032

出　　处：《中国临床医学》2023年第4期697-702,共6页Chinese Journal of Clinical Medicine

基　　金：厦门市恶性肿瘤综合治疗临床医学研究中心项目.

摘　　要：目的探讨原发性咽旁间隙肿瘤的临床特征。方法回顾性选择2010年3月至2018年8月复旦大学附属中山医院收治的30例原发性咽旁间隙肿瘤患者,分析其症状、体征、CT和MRI表现、手术入路、术后病理及并发症等。结果男性13例,女性17例,年龄22~78岁,平均年龄(44.3±15.4)岁。21例患者无明显症状,因发现颈部肿块就诊。神经鞘瘤、多形性腺瘤、副神经节瘤和其他类型肿瘤的CT/MRI表现检查可以有效显示肿瘤大小、部位及其与周围组织的关系。30例患者肿瘤均行手术切除,其中26例经颈入路。病理结果显示良性29例,其中神经鞘瘤13例,多形性腺瘤10例。术后出现声带麻痹4例、Horner综合征3例、面瘫2例、伸舌偏斜1例、抬肩困难1例。随访患者无复发或转移。结论咽旁间隙肿瘤患者大多无明显症状,CT/MRI有助于其诊断及手术径路的选择,神经鞘瘤和多形性腺瘤是其最常见的病理类型。Objective To explore the clinical features of primary parapharyngeal space(PPS)tumors.Methods The case data of 30 patients with primary PPS tumors admitted to Zhongshan Hospital,Fudan University from March 2010 to August 2018 were retrospectively selected,and their symptoms,signs,CT and MRI manifestations,surgical approaches,postoperative pathology and complications were analyzed.Results There were 13 males and 17 females,aged 22-78 years,with an average age of(44.3±15.4)years.21 patients showed no obvious symptoms and sought medical attention due to the discovery of a neck lump.CT/MRI findings of schwannoma,pleomorphic adenoma,paraganglioma and other types of tumors can effectively show the size and location of the tumor and its relationship with surrounding tissues.All 30 patients underwent surgical resection of the tumor,of which 26 underwent a cervical approach.The pathological results showed 29 cases of benign tumors,including 13 cases of schwannoma and 10 cases of pleomorphic adenoma.Postoperative vocal cord paralysis occurred in 4 cases,Horner’s syndrome in 3 cases,facial paralysis in 2 cases,tongue deviation in 1 case,and difficulty lifting the shoulder in 1 case.There was no recurrence or metastasis in the follow-up patients.Conclusion Most PPS tumor patients have no obvious symptoms.CT/MRI is helpful for diagnosis and selection of surgical approach.Schwannoma and pleomorphic adenoma are the most common pathological types.

关 键 词：咽旁间隙肿瘤 电子计算机断层扫描 磁共振成像 手术 

分 类 号：R739.6[医药卫生—肿瘤]